{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T15:26:58Z","timestamp":1791559618729,"version":"4.3.4"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,9,26]],"date-time":"2019-09-26T00:00:00Z","timestamp":1569456000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Evaluation of<jats:italic>Helicobacter pylori<\/jats:italic>infection status (non\u2010infection, past infection, current infection) has become important. This study aimed to determine the usefulness of the Kyoto classification of gastritis for diagnosing<jats:italic>H.\u00a0pylori<\/jats:italic>infection status by endoscopy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this prospective study, 498 subjects were recruited. Seven well\u2010experienced endoscopists blinded to the history of eradication therapy performed the examinations. Endoscopic findings were assessed according to the Kyoto classification of gastritis: diffuse redness, regular arrangement of collecting venules (<jats:styled-content style=\"fixed-case\">RAC<\/jats:styled-content>), fundic gland polyp (<jats:styled-content style=\"fixed-case\">FGP<\/jats:styled-content>), atrophy, xanthoma, hyperplastic polyp, map\u2010like redness, intestinal metaplasia, nodularity, mucosal swelling, white and flat elevated lesion, sticky mucus, depressive erosion, raised erosion, red streak, and enlarged folds. We established prediction models according to a machine learning procedure and compared them with general assessment by endoscopists using the Kyoto classification of gastritis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Significantly higher diagnostic odds were obtained for<jats:styled-content style=\"fixed-case\">RAC<\/jats:styled-content>(32.2),<jats:styled-content style=\"fixed-case\">FGP<\/jats:styled-content>(7.7), and red streak (4.7) in subjects with non\u2010infection, map\u2010like redness (12.9) in subjects with past infection, and diffuse redness (26.8), mucosal swelling (13.3), sticky mucus (10.2) and enlarged fold (8.6) in subjects with current infection. The overall diagnostic accuracy rate was 82.9% with the Kyoto classification of gastritis. The diagnostic accuracy of the prediction model was 88.6% for the model without<jats:italic>H.\u00a0pylori<\/jats:italic>eradication history and 93.4% for the model with eradication history.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The Kyoto classification of gastritis is useful for diagnosing<jats:italic>H.\u00a0pylori<\/jats:italic>infection status based on endoscopic findings. Our prediction model is helpful for novice endoscopists. (<jats:styled-content style=\"fixed-case\">UMIN<\/jats:styled-content>000016674).<\/jats:p><\/jats:sec>","DOI":"10.1111\/den.13486","type":"journal-article","created":{"date-parts":[[2019,7,16]],"date-time":"2019-07-16T01:49:17Z","timestamp":1563241757000},"page":"74-83","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":117,"title":["Validity of endoscopic features for the diagnosis of<i>Helicobacter pylori<\/i>infection status based on the Kyoto classification of gastritis"],"prefix":"10.1111","volume":"32","author":[{"given":"Shinji","family":"Yoshii","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Sapporo Medical Center NTT EC Hokkaido Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuhiro","family":"Mabe","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Hakodate National Hospital Hokkaido Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiko","family":"Watano","sequence":"additional","affiliation":[{"name":"Medical Check\u2010up Center Sapporo Medical Center NTT EC Hokkaido Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayoshi","family":"Ohno","sequence":"additional","affiliation":[{"name":"Division of Endoscopy Hokkaido University Hospital Hokkaido Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mio","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Hokkaido Medical Center Hokkaido Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoko","family":"Ono","sequence":"additional","affiliation":[{"name":"Division of Endoscopy Hokkaido University Hospital Hokkaido Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiko","family":"Kudo","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Health Sciences University of Hokkaido Hospital Hokkaido Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanori","family":"Nojima","sequence":"additional","affiliation":[{"name":"Center for Translational Research The Institute of Medical Science Hospital The University of Tokyo Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mototsugu","family":"Kato","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Hakodate National Hospital Hokkaido Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoya","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Hokkaido University Graduate School of Medicine Hokkaido"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,9,26]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000339176"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-5378.2011.00889.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa001999"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2005.02459.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)61159-9"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.15.4290"},{"key":"e_1_2_7_8_1","unstructured":"Research Center for Cancer Prevention and Screening.National Cancer Center: Japanese guidelines for gastric cancer screening.2014. 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