{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T11:17:55Z","timestamp":1782731875128,"version":"3.54.5"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,8,20]],"date-time":"2019-08-20T00:00:00Z","timestamp":1566259200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:p>Over\u2010the\u2010scope clip (<jats:styled-content style=\"fixed-case\">OTSC<\/jats:styled-content>) has been reported to control non\u2010variceal bleeding; however, the use of this device for acute variceal hemorrhage (<jats:styled-content style=\"fixed-case\">AVH<\/jats:styled-content>) is very limited. We report our experience regarding the use of <jats:styled-content style=\"fixed-case\">OTSC<\/jats:styled-content> in patients with <jats:styled-content style=\"fixed-case\">AVH<\/jats:styled-content> in terms of technical success and safety. A retrospective clinical experience case series study was conducted from October 2017 to June 2019 at two tertiary care centers. Adult patients with <jats:styled-content style=\"fixed-case\">AVH<\/jats:styled-content> as a result of small varices managed with <jats:styled-content style=\"fixed-case\">OTSC<\/jats:styled-content> after endoscopic band ligation (<jats:styled-content style=\"fixed-case\">EBL<\/jats:styled-content>) failure were enrolled. Standard gastroscope and <jats:styled-content style=\"fixed-case\">OTSC<\/jats:styled-content> \u2018type a\u2019 with a cap of 11\u00a0mm in diameter were used in all procedures. Total of five patients with chronic liver disease (Child\u2010Pugh score \u22648) and portal hypertension (hepatic venous pressure gradient, mean 14.4\u00a0\u00b1\u00a01.3\u00a0mmHg) were included. Four of them presented collapse of the bleeding varix, and one had wall disruption associated with fibrosis secondary to prior banding. We were able to stop <jats:styled-content style=\"fixed-case\">AVH<\/jats:styled-content> in all patients without clip\u2010related adverse events during a 30\u2010day follow\u2010up period. Two patients developed solid food dysphagia after 3\u00a0months of clip deployment that resolved after removal using a bipolar cutting device. Twin grasper or anchor were not used to aid or facilitate the approximation of opposite edges in any patient. No additional local therapies or new endoscopic session for variceal eradication were required. This case series shows preliminary success controlling <jats:styled-content style=\"fixed-case\">AVH<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\">OTSC<\/jats:styled-content> after <jats:styled-content style=\"fixed-case\">EBL<\/jats:styled-content> failure in patients with small varices. Esophageal dysphagia may appear as a complication during follow up but it can be resolved by clip removal.<\/jats:p>","DOI":"10.1111\/den.13493","type":"journal-article","created":{"date-parts":[[2019,7,22]],"date-time":"2019-07-22T18:18:22Z","timestamp":1563819502000},"page":"712-716","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Over\u2010the\u2010scope clip for acute esophageal variceal bleeding"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2611-1051","authenticated-orcid":false,"given":"Carolina","family":"Mangas\u2010Sanjuan","sequence":"first","affiliation":[{"name":"Endoscopy Unit Alicante University General Hospital Alicante Institute for Health and Biomedical Research, ISABIAL Alicante Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bel\u00e9n","family":"Mart\u00ednez-Moreno","sequence":"additional","affiliation":[{"name":"Endoscopy Unit 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