{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T11:40:40Z","timestamp":1790250040481,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,12,20]],"date-time":"2019-12-20T00:00:00Z","timestamp":1576800000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Risk stratification is recommended in all patients with acute variceal bleeding (AVB). It remains unclear whether liver disease severity or upper gastrointestinal bleeding (UGIB) scoring algorithms offer superior predictive ability. We aimed to validate the AIMS65 score as a predictor of mortality in AVB, and to compare AIMS65 with established UGIB and liver disease severity risk stratification scores.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>International Classification of Diseases, Tenth Revision codes identified patients presenting with AVB to three tertiary centers over a 48\u2010month period. Patients were risk\u2010stratified using AIMS65, Rockall, pre\u2010endoscopy Rockall, Child\u2010Pugh, Model for End\u2010stage Liver Disease (MELD) and United Kingdom MELD (UKELD) scores. Primary outcomes were inpatient and 6\u2010week mortality and inpatient rebleeding.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two hundred and twenty\u2010three patients were included. Inpatient and 6\u2010week mortality were 13.9% and 15.5% respectively. Prediction of inpatient mortality by AIMS65 (area under the receiver\u2010operating characteristic curve [AUROC: 0.84]) was equivalent to UGIB (Rockall: 0.79, pre\u2010Rockall: 0.78) and liver risk scores (MELD: 0.81, UKELD: 0.79, Child\u2010Pugh: 0.78). AIMS65 score \u22653 best defined high\u2010 and low\u2010risk groups for inpatient mortality (mortality 37.7% <jats:italic>vs<\/jats:italic> 4.9%). AIMS65 (AUROC: 0.62) was equivalent to UGIB risk scores (pre\u2010Rockall: 0.64, Rockall: 0.70) in predicting inpatient rebleeding and superior to liver risk scores (MELD: 0.56, UKELD: 0.57, Child\u2010Pugh: 0.60).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>AIMS65 is equivalent to established UGIB and liver disease severity risk stratification scores in predicting mortality, and superior to liver scores in predicting rebleeding.<\/jats:p><\/jats:sec>","DOI":"10.1111\/den.13577","type":"journal-article","created":{"date-parts":[[2019,11,4]],"date-time":"2019-11-04T08:50:24Z","timestamp":1572857424000},"page":"761-768","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Risk stratification in acute variceal bleeding: Comparison of the AIMS65 score to established upper gastrointestinal bleeding and liver disease severity risk stratification scoring systems in predicting mortality and rebleeding"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8848-1771","authenticated-orcid":false,"given":"Marcus","family":"Robertson","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Liver Transplant Unit Austin Hospital Heidelberg Australia"},{"name":"Department of Gastroenterology Monash Health Clayton Australia"},{"name":"Department of Medicine School of Clinical Sciences Monash University Clayton Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Ng","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Monash Health Clayton Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walid","family":"Abu Shawish","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Monash Health Clayton 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