{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T07:17:58Z","timestamp":1780730278564,"version":"3.54.1"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T00:00:00Z","timestamp":1598572800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Peroral endoscopic myotomy with fundoplication (POEM\u2010F) has garnered widespread attention since it tries to achieve an appropriate antireflux procedure during the same setting. The outcomes of POEM\u2010F are currently unexplored.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients who underwent POEM\u2010F at our center were retrospectively studied to assess its safety and early outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty patients [70% male; median age 32\u00a0years (range 25\u201341)], with a median symptom duration of 2.1\u00a0years (range 1.5\u20133.7) with achalasia were included. POEM\u2010F procedure was completed in a median of 118\u00a0min (range 90\u2013160), with 17\/20 (85%) technical success. The median hospitalization was 4\u00a0days (range 2\u20137). Capnothorax (<jats:italic>n<\/jats:italic>\u00a0=\u00a03), resolved spontaneously (<jats:italic>n<\/jats:italic>\u00a0=\u00a02) in 4\u20136\u00a0h, while in one patient (<jats:italic>n<\/jats:italic>\u00a0=\u00a01) the endoscope inadvertently entered into the thoracic cavity for which prophylactic intercostal drain was required. Capnoperitoneum was seen in 17\/17 (100%) patients who underwent fundoplication, subcutaneous emphysema in 8\/17 (47%) patients. At 1\u2010month follow\u2010up endoscopy, 5\/17 (29.4%) patients had loosening of the fundal wrap, 3\/17 (17.6%) patients had ulceration in fundus and in gastroesophageal junction due to underlying hemoclips. At 3\u00a0months, loosening of the fundal wrap was seen in 7\/17 (41.2%) patients. A 24\u2010h pH\u2010metry revealed abnormal esophageal acid exposure in 7\/17 (41.2%) patients, while it was normal in those patients in whom the fundal wrap was maintained. 10\/17 (58.8%) patients were off proton pump inhibitors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>POEM\u2010F is technically feasible with reasonable short term success. However, the durability, early success and safety of POEM\u2010F need reassessment in long\u2010term studies before being applied in clinical practice.<\/jats:p><\/jats:sec>","DOI":"10.1111\/den.13796","type":"journal-article","created":{"date-parts":[[2020,7,21]],"date-time":"2020-07-21T10:19:36Z","timestamp":1595326776000},"page":"561-568","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Early outcomes of peroral endoscopic myotomy with fundoplication for achalasia cardia \u2013 Is it here to stay?"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9346-4343","authenticated-orcid":false,"given":"Gaurav","family":"Patil","sequence":"first","affiliation":[{"name":"Baldota Institute of Digestive Sciences Gleneagles Global Hospital Mumbai 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