{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T10:42:38Z","timestamp":1780742558693,"version":"3.54.1"},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,10,28]],"date-time":"2020-10-28T00:00:00Z","timestamp":1603843200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The regular arrangement of collecting venules (RAC) and the Kimura\u2010Takemoto classification of atrophic change (KTC) are simple and easy\u2010to\u2010use criteria which have been shown to reliably predict or rule out a <jats:italic>Helicobacter pylori<\/jats:italic> infection of the stomach. Although these features have been investigated extensively in Asia, their significance in the West has not been evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In a series of 200 consecutive gastroscopic examinations (single examiner, single center), the presence or absence of RAC and the KTC grade (open type vs closed type) were recorded prospectively. <jats:italic>Helicobacter pylori<\/jats:italic> infection was defined as a positive histology or a positive rapid urease test. Furthermore, multivariate analysis of endoscopic predictors of <jats:italic>H.\u00a0pylori<\/jats:italic> infection based on the Kyoto classification of gastritis was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two hundred patients were examined of which 57 had a <jats:italic>H.\u00a0pylori<\/jats:italic> infection (28%). Both RAC and KTC had excellent negative predictive values of about 90% and sensitivity values of up to 85%. In multivariate analysis, atrophic change and diffuse redness without RAC were significantly associated with <jats:italic>H.\u00a0pylori<\/jats:italic> infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Regular arrangement of collecting venules and KTC are simple endoscopic features which should be given attention by Western endoscopists and can be easily used to rule out a <jats:italic>H.\u00a0pylori<\/jats:italic> infection of the stomach.<\/jats:p><\/jats:sec>","DOI":"10.1111\/den.13808","type":"journal-article","created":{"date-parts":[[2020,8,8]],"date-time":"2020-08-08T05:41:35Z","timestamp":1596865295000},"page":"587-591","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Regular arrangement of collecting venules and the Kimura\u2010Takemoto classification for the endoscopic diagnosis of <i>Helicobacter pylori<\/i> infection: Evaluation in a Western setting"],"prefix":"10.1111","volume":"33","author":[{"given":"Alanna","family":"Ebigbo","sequence":"first","affiliation":[{"name":"Department of Gastroenterology University Hospital Augsburg Augsburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rg","family":"Marienhagen","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Augsburg Augsburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helmut","family":"Messmann","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology University Hospital Augsburg Augsburg 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