{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T05:23:29Z","timestamp":1788326609821,"version":"build-2803163510"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T00:00:00Z","timestamp":1629072000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Hepaticojejunostomy anastomotic stricture (HJAS) is a significant complication of biliary reconstruction surgery. Endoscopic management of HJAS using double\u2010balloon enteroscopy has expanded; however, retrospective reports in this setting are limited. This study aimed to evaluate the efficacy of endoscopic balloon dilatation combined with stent deployment for HJAS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a single\u2010arm prospective clinical trial involving 40 patients with treatment\u2010na\u00efve HJAS enrolled between March 2016 and August 2019 at four endoscopy units in Japan. For HJAS, plastic stents combined with balloon dilatation were placed for 6\u2009months after initial stenting. The primary outcome was HJ anastomosis patency 12\u2009months after stent removal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The technical success rate was 97.5% (39\/40). The failed case required percutaneous transhepatic biliary drainage using the rendezvous technique. All cases achieved successful endoscopic treatment. During the treatment period, four of 40 patients (10%) ended the study protocol due to unrelated causes and were excluded from the primary analysis. Among the 36 patients, clinical success was achieved in 34 (94.4%) patients. The remaining two patients achieved HJAS resolution after an additional 3\u2009months. All 36 patients achieved HJAS resolution. Adverse events were observed in two patients (5.0%) who developed moderate cholangitis. During a median follow\u2010up of 21.3\u2009months, HJAS recurrence was observed in 8.3% (3\/36) with a median time to recurrence of 4.3\u2009months and HJ anastomosis patency at 12\u2009months was 94.4%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Endoscopic balloon dilatation combined with plastic stent deployment for 6\u2009months was a safe and effective strategy for HJAS. (Clinical Trial Registry no. UMIN000020613).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/den.14097","type":"journal-article","created":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T15:08:36Z","timestamp":1627571316000},"page":"604-611","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Efficacy of double\u2010balloon enteroscopy\u2010assisted endoscopic balloon dilatation combined with stent deployment for hepaticojejunostomy anastomotic stricture"],"prefix":"10.1111","volume":"34","author":[{"given":"Takeshi","family":"Tomoda","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology Okayama University Hospital Okayama Japan"},{"name":"Department of Gastroenterology Okayama City Hospital Okayama 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