{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T18:47:54Z","timestamp":1760986074476,"version":"3.40.5"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,10,13]],"date-time":"2021-10-13T00:00:00Z","timestamp":1634083200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Early feeding was previously considered to increase the risk of postprocedural bleeding. However, many trials have demonstrated the benefits of early feeding after therapeutic endoscopic procedures. We conducted a meta\u2010analysis of randomized controlled trials to evaluate the safety and outcomes between early feeding and delayed feeding after therapeutic endoscopic procedures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Medline (PubMed), Embase, Google Scholar, the Cochrane Library, and clinicaltrials.gov were searched to identify randomized controlled trials that met our inclusion criteria. The pooled data for the mortality rate, postprocedural bleeding rate, and length of hospital stay were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of seven trials consisting of 717 patients were reviewed. These seven trials examined various therapeutic endoscopic procedures. Three trials included patients undergoing endoscopic hemostasis for upper gastrointestinal bleeding, two included patients undergoing esophageal variceal ligation, and two included patients with gastric neoplasm treated with endoscopic submucosal dissection. Although no significant differences were observed in the postprocedural bleeding rate or the mortality rate between patients who received early feeding and those who received delayed feeding,\u2009early feeding resulted in shorter hospital stays (weighted mean difference \u22121.04, 95% confidence interval \u22121.45 to 0.63).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Early feeding appears to be a safe management method for patients undergoing therapeutic endoscopic procedures. Therefore, we recommend early feeding for these patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/den.14140","type":"journal-article","created":{"date-parts":[[2021,9,18]],"date-time":"2021-09-18T21:55:42Z","timestamp":1632002142000},"page":"451-458","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Early versus delayed feeding after therapeutic endoscopic procedures: Meta\u2010analysis of randomized controlled trials"],"prefix":"10.1111","volume":"34","author":[{"given":"Sheau Wen","family":"Kan","sequence":"first","affiliation":[{"name":"Division of Emergency Medicine Department of Emergency and Critical Care Taipei Medical University\u2013Shuang Ho Hospital New Taipei City Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ting\u2010Yun","family":"Huang","sequence":"additional","affiliation":[{"name":"Division of Emergency Medicine Department of Emergency and Critical Care Taipei Medical University\u2013Shuang Ho Hospital New Taipei City Taiwan"},{"name":"Department of Emergency School of Medicine College of Medicine Taipei Medical University New Taipei City Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hon\u2010Ping","family":"Ma","sequence":"additional","affiliation":[{"name":"Division of Emergency Medicine Department of Emergency and Critical Care Taipei Medical University\u2013Shuang Ho Hospital New Taipei City Taiwan"},{"name":"Graduate Institute of Injury Prevention and Control College of Public Health and Nutrition Taipei Medical University New Taipei City Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming Zhe","family":"Tay","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology Department of Internal Medicine Taipei Medical University\u2013Shuang Ho Hospital New Taipei City Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ka\u2010Wai","family":"Tam","sequence":"additional","affiliation":[{"name":"Division of General Surgery Department of Surgery Taipei Medical University\u2013Shuang Ho Hospital New Taipei City Taiwan"},{"name":"Division of General Surgery Department of Surgery School of Medicine College of Medicine Taipei Medical University New Taipei City Taiwan"},{"name":"Cochrane Taiwan Taipei Medical University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9592-3278","authenticated-orcid":false,"given":"Tung\u2010Yao","family":"Tsai","sequence":"additional","affiliation":[{"name":"Division of Emergency Medicine Department of Emergency and Critical Care Taipei Medical University\u2013Shuang Ho Hospital New Taipei City Taiwan"},{"name":"Department of Emergency School of Medicine College of Medicine Taipei Medical University New Taipei City 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