{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T12:53:54Z","timestamp":1792155234168,"version":"4.4.0"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,2,21]],"date-time":"2024-02-21T00:00:00Z","timestamp":1708473600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this study was to compare endoscopic ultrasound\u2010guided choledochoduodenostomy (EUS\u2010CDS) vs. EUS\u2010gallbladder drainage (EUS\u2010GBD) in cases of failed endoscopic retrograde cholangiopancreatography (ERCP) for jaundice resulting from malignant distal biliary obstruction (MDBO).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This multicenter retrospective study included patients with obstructive jaundice secondary to MDBO who underwent EUS\u2010GBD or EUS\u2010CDS with lumen\u2010apposing metal stents after failed ERCP. The primary end\u2010point was clinical success rate. Secondary end\u2010points were technical success, periprocedural adverse events rate (&lt;24\u2009h), late adverse events rate (&gt;24\u2009h), overall survival, and time to recurrent biliary obstruction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 78 patients were included: 41 underwent EUS\u2010GBD and 37 underwent EUS\u2010CDS. MDBO was mainly the result of pancreatic cancer (<jats:italic>n<\/jats:italic>\u2009=\u200963\/78, 80.7%). Clinical success rate was similar for both procedures: 87.8% for EUS\u2010GBD and 89.2% for EUS\u2010CDS (<jats:italic>P<\/jats:italic>\u2009=\u20090.8). Technical success rate was 100% for EUS\u2010GBD and 94.6% for EUS\u2010CDS (<jats:italic>P<\/jats:italic>\u2009=\u20090.132). Periprocedural morbidity (&lt;24\u2009h) rates were similar between both groups: 4\/41 (9.8%) for EUS\u2010GBD and 5\/37 (13.5%) for EUS\u2010CDS (<jats:italic>P<\/jats:italic>\u2009=\u20090.368). There was a significantly higher rate of late morbidity (&gt;24\u2009h) among patients in the EUS\u2010CDS group (8\/37 [21.6%]) than in the EUS\u2010GBD group (3\/41 [7.3%]) (<jats:italic>P<\/jats:italic>\u2009=\u20090.042). The median follow\u2010up duration was 4.7\u2009months. Overall survival and time to recurrent biliary obstruction did not significantly differ between the groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>After failed ERCP for MDBO, EUS\u2010GBD and EUS\u2010CDS show comparable clinical success rates and technical success. EUS\u2010GBD appears to be a promising alternative for MDBO, even as a second\u2010line treatment after failed ERCP. Further studies are needed to validate these findings and compare the long\u2010term outcomes of EUS\u2010GBD and EUS\u2010CDS.<\/jats:p><\/jats:sec>","DOI":"10.1111\/den.14750","type":"journal-article","created":{"date-parts":[[2024,2,21]],"date-time":"2024-02-21T09:55:08Z","timestamp":1708509308000},"page":"103-114","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Effectiveness of endoscopic ultrasound (EUS)\u2010guided choledochoduodenostomy vs. EUS\u2010guided gallbladder drainage for jaundice in patients with malignant distal biliary obstruction after failed endoscopic retrograde cholangiopancreatography: Retrospective, multicenter study (GALLBLADEUS Study)"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3785-6948","authenticated-orcid":false,"given":"Antoine","family":"Debourdeau","sequence":"first","affiliation":[{"name":"Hepatogastroenterology Department Nimes University Hospital, University of Montpellier  Nimes France"},{"name":"Hepatogastroenterology Department Montpellier University Hospital, University of Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jules","family":"Daniel","sequence":"additional","affiliation":[{"name":"Hepatogastroenterology Department Nimes University Hospital, University of Montpellier  Nimes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ludovic","family":"Caillo","sequence":"additional","affiliation":[{"name":"Hepatogastroenterology Department Nimes University Hospital, University of Montpellier  Nimes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Assenat","sequence":"additional","affiliation":[{"name":"Hepatogastroenterology Department Montpellier University Hospital, University of Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Bertrand","sequence":"additional","affiliation":[{"name":"Surgery Department Nimes University Hospital, University of Montpellier  Nimes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Bardol","sequence":"additional","affiliation":[{"name":"Surgery Department Montpellier University Hospital, University of Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois\u2010R\u00e9gis","family":"Souche","sequence":"additional","affiliation":[{"name":"Surgery Department Montpellier University Hospital, University of Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Pouderoux","sequence":"additional","affiliation":[{"name":"Hepatogastroenterology Department Nimes University Hospital, University of Montpellier  Nimes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romain","family":"Gerard","sequence":"additional","affiliation":[{"name":"Hepatogastroenterology Department Lille University Hospital, Lille University  Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane","family":"Lorenzo","sequence":"additional","affiliation":[{"name":"Hepatogastroenterology Department Beaujon University Hospital, Paris Cit\u00e9 University  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Fran\u00e7ois","family":"Bourgaux","sequence":"additional","affiliation":[{"name":"Hepatogastroenterology Department Nimes University Hospital, University of Montpellier  Nimes 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