{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T21:03:31Z","timestamp":1791839011637,"version":"4.3.4"},"reference-count":31,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T00:00:00Z","timestamp":1737331200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The endoscopic pressure study integrated system (EPSIS) measures intragastric pressure (IGP) during esophagogastroduodenoscopy. Previous research demonstrated that EPSIS correlates with the 24\u2010h impedance\u2010pH (MII\u2010pH) test and shows lower maximum IGP (IGP\u2010Max) and a flatter waveform gradient in gastroesophageal reflux disease (GERD) patients, attributed to lower esophageal sphincter dysfunction. Although endoscopic antireflux therapy (EARTh) is effective for GERD, the MII\u2010pH monitoring, the gold standard for assessing treatment outcomes, requires hospitalization and can be a burden. EPSIS offers a noninvasive alternative for evaluating post\u2010EARTh outcomes. This study aimed to assess EPSIS as an additional diagnostic tool in this context.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective analysis of GERD patients who underwent EARTh and were subsequently assessed using EPSIS within 6\u2009months, from May 2018 to April 2024. Changes in IGP parameters, including IGP\u2010Max and waveform gradient, were analyzed pre\u2010 and post\u2010EARTh. Additionally, the study examined Hill's Classification following EARTh.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Out of 39 patients assessed with EPSIS before and after EARTh, the average age was 55\u2009years (standard deviation [SD] 16.7), with 64.1% male. Postoperative IGP\u2010Max increased from 15.2\u2009mmHg to 18.0\u2009mmHg (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.004), and the pressure gradient improved from 0.16\u2009mmHg\/s to 0.28\u2009mmHg\/s (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001). Hill's Classification improved significantly from a mean of 2.2 (SD 0.7) to 1.1 (SD 0.3) (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study indicates that EPSIS is a reliable diagnostic tool for evaluating the effects of EARTh and holds potential as a supplementary tool for assessing GERD treatment outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/den.14989","type":"journal-article","created":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T23:32:31Z","timestamp":1737415951000},"page":"670-679","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Utility of endoscopic pressure study integrated system for gastroesophageal reflux disease after endoscopic antireflux therapy"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6614-2763","authenticated-orcid":false,"given":"Kazuki","family":"Yamamoto","sequence":"first","affiliation":[{"name":"Digestive Diseases Center Showa University Koto Toyosu Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruhiro","family":"Inoue","sequence":"additional","affiliation":[{"name":"Digestive Diseases Center Showa University Koto Toyosu Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8776-6663","authenticated-orcid":false,"given":"Ippei","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Digestive Diseases Center Showa University Koto Toyosu Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei","family":"Ushikubo","sequence":"additional","affiliation":[{"name":"Digestive Diseases Center Showa University Koto 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Center Showa University Koto Toyosu Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0962-8342","authenticated-orcid":false,"given":"Satoshi","family":"Abiko","sequence":"additional","affiliation":[{"name":"Digestive Diseases Center Showa University Koto Toyosu Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boldbaatar","family":"Gantuya","sequence":"additional","affiliation":[{"name":"Digestive Diseases Center Showa University Koto Toyosu Hospital  Tokyo Japan"},{"name":"Department of Gastroenterology Mongolian National University of Medical Sciences  Ulaanbaatar Mongolia"},{"name":"Endoscopy Unit Mongolia Japan Hospital  Ulaanbaatar Mongolia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manabu","family":"Onimaru","sequence":"additional","affiliation":[{"name":"Digestive Diseases Center Showa University Koto Toyosu Hospital  Tokyo 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