{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T11:49:05Z","timestamp":1787226545353,"version":"build-2736575974"},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Percutaneous transhepatic liver abscess drainage (PTAD) and endoscopic ultrasound\u2010guided liver abscess drainage (EUS\u2010LAD) have several limitations. Recently, because of technical improvements in echoendoscope maneuvers, EUS\u2010guided access for the right hepatic lobe has been reported. The aim of this multicenter, retrospective study was to compare clinical outcomes of PTAD and EUS\u2010LAD including the right hepatic lobe in West Japan.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>This retrospective, multicenter study included consecutive patients with liver abscesses between January 2019 and November 2024. The primary outcome in this study was the clinical success rate compared between EUS\u2010LAD and PTAD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      During the study period, 1012 consecutive patients developed liver abscesses. Of them, 734 patients were excluded, 43 underwent EUS\u2010LAD and 235 patients underwent PTAD. After propensity score\u2010matched analysis, the clinical success rate was significantly higher in the EUS\u2010LAD group (97.7%, 42\/43) than in the PTAD group (79.1%, 34\/43) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.007). After a propensity score\u2010matched analysis, 25 patients were included in each group. The clinical success rate was significantly higher in the EUS\u2010LAD group (100%, 25\/25) than in the PTAD group (84%, 21\/25) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.037). Adverse events were also significantly higher in the PTAD group (16%, 5\/25) than in the EUS\u2010LAD group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.025). In addition, the median length of hospital stay was significantly shorter in the EUS\u2010LAD group (15\u2009days) than in the PTAD group (22\u2009days) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>EUS\u2010LAD using a metal stent might be one of the options, but further randomized, controlled trials are needed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/den.70067","type":"journal-article","created":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T12:36:43Z","timestamp":1764247003000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["<scp>EUS<\/scp>\n                    \u2010Guided Versus Percutaneous Transhepatic Drainage of Liver Abscesses: A Multicenter Endohepatology Study in Western Japan (\n                    <scp>EPIC<\/scp>\n                    \u2010\n                    <scp>LA<\/scp>\n                    Study)"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2916-6568","authenticated-orcid":false,"given":"Takeshi","family":"Ogura","sequence":"first","affiliation":[{"name":"Pancreatobiliary Advanced Medical Center Osaka Medical and Pharmaceutical University Hospital  Osaka Japan"},{"name":"Endoscopy Center Osaka Medical and Pharmaceutical University Hospital  Osaka Japan"},{"name":"2nd Department of Internal Medicine Osaka Medical and Pharmaceutical University  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taira","family":"Kuroda","sequence":"additional","affiliation":[{"name":"Gastroenterology Center Ehime Prefectural Hospital  Matsuyama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takanori","family":"Matsuura","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine Kobe University Graduate School of Medicine  Kobe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Kitadai","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine Kobe University Graduate School of Medicine  Kobe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5794-1512","authenticated-orcid":false,"given":"Koh","family":"Kitagawa","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Nara Medical University  Kashihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Itonaga","sequence":"additional","affiliation":[{"name":"Second Department of Internal Medicine Wakayama Medical University  Wakayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kotaro","family":"Takeshita","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Tane General Hospital  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoaki","family":"Matsumori","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Kyoto University Graduate School of Medicine  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoya","family":"Emori","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Wakayama Rosai Hospital  Wakayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7308-4311","authenticated-orcid":false,"given":"Mamoru","family":"Takenaka","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Kindai University Faculty of Medicine Graduate School of Medical Sciences  Osakasayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajime","family":"Imai","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Okanami General Hospital  Iga Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3039-2303","authenticated-orcid":false,"given":"Koichiro","family":"Mandai","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Kyoto Second Red Cross Hospital  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuhei","family":"Shintani","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Shiga University of Medical Science  Otsu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4286-8804","authenticated-orcid":false,"given":"Nao","family":"Fujimori","sequence":"additional","affiliation":[{"name":"Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences Kyushu University  Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7461-8538","authenticated-orcid":false,"given":"Hideyuki","family":"Shiomi","sequence":"additional","affiliation":[{"name":"Division of Hepatobiliary and Pancreatic Diseases, Department of Gastroenterology Hyogo Medical University  Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanori","family":"Asada","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Japanese Red Cross Osaka Hospital  Osaka 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Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6911-7686","authenticated-orcid":false,"given":"Masaaki","family":"Shimatani","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Kansai Medical University Medical Center  Moriguchi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidefumi","family":"Nishikiori","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Oita San\u2010ai Medical Center  Oita Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5102-7452","authenticated-orcid":false,"given":"Kazuyuki","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"Department of Endoscopy Okayama University Hospital  Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahito","family":"Kokubu","sequence":"additional","affiliation":[{"name":"Department of 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