{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T02:26:22Z","timestamp":1779330382938,"version":"3.51.4"},"reference-count":36,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:00:00Z","timestamp":1772150400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:00:00Z","timestamp":1772150400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["24K15801"],"award-info":[{"award-number":["24K15801"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Enteroscopy\u2010assisted endoscopic retrograde pancreatography\u2010guided pancreatic duct drainage (eERP\u2010PDD) and endoscopic ultrasound\u2010guided pancreatic duct drainage (EUS\u2010PDD) are minimally invasive alternatives to surgery for pancreaticojejunostomy stricture (PJS); however, comparative data remain limited. We compared the effectiveness and safety of these approaches and identified factors associated with technical failure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This multicenter retrospective study included 88 patients (111 procedures) who underwent endoscopic intervention for PJS at 13 Japanese tertiary centers. We compared clinical outcomes between eERP\u2010PDD and EUS\u2010PDD. The primary outcome was technical success; secondary outcomes included clinical success, procedure time, and adverse events (AEs). Propensity\u2010score overlap weighting was used to adjust for baseline differences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      As initial treatment, 77 patients underwent eERP\u2010PDD and 11 underwent EUS\u2010PDD. After adjustment, EUS\u2010PDD achieved higher technical success (eERP\u2010PDD, 28% vs. EUS\u2010PDD, 71%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.012) and clinical success (22% vs. 71%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003), with shorter procedure time (76\u2009min vs. 41\u2009min;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001). AE incidence was higher with EUS\u2010PDD before adjustment (5% vs. 27%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.039) but comparable after adjustment (7% vs. 29%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.15); all AEs resolved with conservative management. Age\u2009&lt;\u200975\u2009years, male sex, and main pancreatic duct (MPD) diameter \u2265\u20095\u2009mm were independently associated with eERP\u2010PDD failure.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>EUS\u2010PDD demonstrated higher technical and clinical success than eERP\u2010PDD for PJS, with comparable safety after adjustment. An MPD diameter \u2265\u20095\u2009mm was associated with eERP\u2010PDD failure. An MPD\u2010based algorithm is proposed: eERP\u2010PDD for MPD &lt;\u20095\u2009mm with EUS\u2010PDD as salvage, and EUS\u2010PDD for MPD \u2265\u20095\u2009mm. This algorithm is hypothesis\u2010generating and requires prospective validation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/den.70128","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T11:49:33Z","timestamp":1772970573000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effectiveness and Safety of Enteroscopy\u2010Assisted\n                    <scp>ERP<\/scp>\n                    \u2010Guided Versus\n                    <scp>EUS<\/scp>\n                    \u2010Guided Pancreatic Duct Drainage for Pancreaticojejunostomy Strictures: A Multicenter Observational Study"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5171-1847","authenticated-orcid":false,"given":"Shogo","family":"Ota","sequence":"first","affiliation":[{"name":"Division of Hepatobiliary and Pancreatic Diseases, Department of Gastroenterology Hyogo Medical University  Nishinomiya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7461-8538","authenticated-orcid":false,"given":"Hideyuki","family":"Shiomi","sequence":"additional","affiliation":[{"name":"Division of Hepatobiliary and Pancreatic Diseases, Department of Gastroenterology Hyogo Medical University  Nishinomiya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuki","family":"Fujii","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Okayama University Hospital  Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuyuki","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Okayama University Hospital  Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masataka","family":"Kano","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Kansai Medical University Medical Center  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6911-7686","authenticated-orcid":false,"given":"Masaaki","family":"Shimatani","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Kansai Medical University Medical Center  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1035-6660","authenticated-orcid":false,"given":"Naoki","family":"Fujita","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Neurology Kagawa University  Miki\u2010cho Kita\u2010gun Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideki","family":"Kamada","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Neurology Kagawa University  Miki\u2010cho Kita\u2010gun Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saori","family":"Ueno","sequence":"additional","affiliation":[{"name":"Second Department of Internal Medicine Osaka Medical and Pharmaceutical University  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2916-6568","authenticated-orcid":false,"given":"Takeshi","family":"Ogura","sequence":"additional","affiliation":[{"name":"Second Department of Internal Medicine Osaka Medical and Pharmaceutical University  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7308-4311","authenticated-orcid":false,"given":"Mamoru","family":"Takenaka","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Faculty of Medicine Kindai University  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kae","family":"Nagao","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine  Kobe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1072-5243","authenticated-orcid":false,"given":"Arata","family":"Sakai","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine  Kobe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuhei","family":"Shintani","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Shiga University of Medical Science  Otsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5837-6575","authenticated-orcid":false,"given":"Osamu","family":"Inatomi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Shiga University of Medical Science  Otsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5794-1512","authenticated-orcid":false,"given":"Koh","family":"Kitagawa","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Nara Medical University  Nara Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1844-2865","authenticated-orcid":false,"given":"Ryota","family":"Nakano","sequence":"additional","affiliation":[{"name":"Division of Hepatobiliary and Pancreatic Diseases, Department of Gastroenterology Hyogo Medical University  Nishinomiya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuhito","family":"Koizumi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine  To\u2010on Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiki","family":"Imamura","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine  To\u2010on Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1372-166X","authenticated-orcid":false,"given":"Akihisa","family":"Ohno","sequence":"additional","affiliation":[{"name":"Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences Kyushu University  Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4286-8804","authenticated-orcid":false,"given":"Nao","family":"Fujimori","sequence":"additional","affiliation":[{"name":"Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences Kyushu University  Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takaaki","family":"Tamura","sequence":"additional","affiliation":[{"name":"Second Department of Internal Medicine Wakayama Medical University  Wakayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsukasa","family":"Miyagahara","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, National Hospital Organization Beppu Medical Center  Beppu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikio","family":"Nakajima","sequence":"additional","affiliation":[{"name":"Emergency and Critical Care Center Tokyo Metropolitan Hiroo Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6885-9223","authenticated-orcid":false,"given":"Masayuki","family":"Kitano","sequence":"additional","affiliation":[{"name":"Second Department of Internal Medicine Wakayama Medical University  Wakayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,27]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-018-3859-x"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1477-2574.2009.00007.x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.5407"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199709000-00004"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.2002.02202.x"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00534-006-1204-3"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.21037\/gs-22-692"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.14605"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2010.10.015"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPA.0b013e3181b65ccd"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/den.13746"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.5946\/ce.2020.173"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1055\/a-1236-3350"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2016.07.030"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/den.12048"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pan.2021.03.021"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2016.07.031"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1055\/a-1200-0199"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2021.11.038"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.7819"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.37737\/ace.25012"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/ags3.12528"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12041626"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/deo2.114"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2023.09.001"},{"key":"e_1_2_10_27_1","first-page":"1753","article-title":"Approaching Pancreatic Duct Through Pancreaticojejunostomy Site With Double Balloon Enteroscope in Patients With Roux\u2010En\u2010Y Anatomy","volume":"60","author":"Park J.\u2010H.","year":"2013","journal-title":"Hepato\u2010Gastroenterology"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/deo2.301"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/den.13519"},{"issue":"2","key":"e_1_2_10_30_1","first-page":"E1062","article-title":"Successful Detection of Choledochojejunal and Pancreaticojejunal Anastomotic Strictures Using a Novel Form of Texture and Color Enhancement Imaging","volume":"54","author":"Toyonaga H.","year":"2022","journal-title":"Endoscopy"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2023.04.009"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1055\/a-1266-7592"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/den.12100"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2009.10.048"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1256333"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2013.05.016"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/jhbp.938"}],"container-title":["Digestive Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/den.70128","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/den.70128","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/den.70128","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T10:46:14Z","timestamp":1774867574000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/den.70128"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,27]]},"references-count":36,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1111\/den.70128"],"URL":"https:\/\/doi.org\/10.1111\/den.70128","archive":["Portico"],"relation":{},"ISSN":["0915-5635","1443-1661"],"issn-type":[{"value":"0915-5635","type":"print"},{"value":"1443-1661","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,27]]},"assertion":[{"value":"2025-10-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70128"}}