{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T18:15:00Z","timestamp":1794334500801,"version":"4.9.0"},"reference-count":33,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:00:00Z","timestamp":1780358400000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Self\u2010expandable metallic stents are widely used for malignant colorectal obstruction, and low axial force (AF) stents have been developed to reduce adverse events. The Niti\u2010S Enteral Colonic Uncovered Stent (MD\/BB type) is a new low\u2010AF stent that maintains a 22\u2009mm outer diameter despite using a 9Fr delivery system. This improves placement performance and reduces adverse events. We aim to evaluate the efficacy and safety of this stent.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this prospective, multicenter clinical study, we assess the efficacy and safety of the low\u2010AF Niti\u2010S MD\/BB stent for colonic stenting. Of the 199 consecutive registered patients who underwent colorectal stenting with the Niti\u2010S MD\/BB stents at 12 centers affiliated with the Japan Colonic Stent Safe Procedure Research Group between February 2019 and March 2023, 193 were included for analysis. The primary endpoint was the clinical success rate. The secondary endpoints included technical success and adverse events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The technical success rate was 98.4% (190\/193), and the clinical success rate was 95.9% (185\/193). In all bridge\u2010to\u2010surgery cases, elective surgery was successfully performed as planned, and no perforations were observed. In palliative cases, three perforations occurred. Seven patients required surgery in the subsequent year due to adverse events. The 1\u2010year stent patency rate in PAL cases was 80.6%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This new low\u2010AF Niti\u2010S MD\/BB stent demonstrated excellent safety and efficacy, with high technical and clinical success rates and a low incidence of adverse events. Thus, low\u2010AF stents may be a safe, user\u2010friendly option for obstructive colorectal cancer.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/den.70185","type":"journal-article","created":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T13:15:34Z","timestamp":1780406134000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A Multicenter Prospective Study on the Safety and Efficacy of the New Low Axial Force Self\u2010Expandable Metallic Stent With Slim Delivery System for Malignant Colorectal Obstruction"],"prefix":"10.1111","volume":"38","author":[{"given":"Takeshi","family":"Mizumoto","sequence":"first","affiliation":[{"name":"Department of Endoscopy NHO Kure Medical Center and Chugoku Cancer Center  Kure Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuzuru","family":"Tamaru","sequence":"additional","affiliation":[{"name":"Department of Endoscopy NHO Kure Medical Center and Chugoku Cancer Center  Kure Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9956-1358","authenticated-orcid":false,"given":"Toshio","family":"Kuwai","sequence":"additional","affiliation":[{"name":"Gastrointestinal Endoscopy and Medicine Hiroshima University Hospital  Hiroshima Japan"},{"name":"Institute for Clinical Research NHO Kure Medical Center and Chugoku Cancer Center  Kure Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6468-9375","authenticated-orcid":false,"given":"Akihisa","family":"Matsuda","sequence":"additional","affiliation":[{"name":"Department of Gastroenterological Surgery Nippon Medical School  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuji","family":"Saito","sequence":"additional","affiliation":[{"name":"Division of Surgery, Gastrointestinal Center Yokohama Shin\u2010Midori General Hospital  Yokohama 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