{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T10:16:29Z","timestamp":1792145789466,"version":"4.4.0"},"reference-count":69,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,11,24]],"date-time":"2019-11-24T00:00:00Z","timestamp":1574553600000},"content-version":"am","delay-in-days":333,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#am"},{"start":{"date-parts":[[2018,12,26]],"date-time":"2018-12-26T00:00:00Z","timestamp":1545782400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["F32-MH107129"],"award-info":[{"award-number":["F32-MH107129"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["K01-MH106805"],"award-info":[{"award-number":["K01-MH106805"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R37-MH101495"],"award-info":[{"award-number":["R37-MH101495"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003986","name":"Jacobs Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003986","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000874","name":"Brain and Behavior Research Foundation","doi-asserted-by":"publisher","award":["23582"],"award-info":[{"award-number":["23582"]}],"id":[{"id":"10.13039\/100000874","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000874","name":"Brain and Behavior Research Foundation","doi-asserted-by":"publisher","award":["23819"],"award-info":[{"award-number":["23819"]}],"id":[{"id":"10.13039\/100000874","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006211","name":"Klingenstein Third Generation Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006211","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Developmental Science"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Exposure to stress has been causally linked to changes in hippocampal volume (HV). Given that the hippocampus undergoes rapid changes in the first years of life, stressful experiences during this period may be particularly important in understanding individual differences in the development of the hippocampus. One hundred seventy\u2010eight early adolescents (ages 9\u201313\u00a0years; 43% male) were interviewed regarding exposure to and age of onset of experiences of stress; the severity of each stressful event was rated by an objective panel. All participants underwent structural magnetic resonance imaging, from which HVs were automatically segmented. Without considering the age of onset for stressful experiences, there was a small but statistically significant negative association of stress severity with bilateral HV. When considering the age of onset, there was a moderate and significant negative association between stress severity during early childhood (through 5 years of age) and HV; there was no association between stress severity during later childhood (age 6\u00a0years and older) and HV. We provide evidence of a sensitive period through 5 years of age for the effects of life stress on HV in adolescence. It will be important in future research to elucidate how reduced HV stemming from early life stress may contribute to stress\u2010related health outcomes.<\/jats:p>","DOI":"10.1111\/desc.12775","type":"journal-article","created":{"date-parts":[[2018,11,24]],"date-time":"2018-11-24T11:19:13Z","timestamp":1543058353000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":108,"title":["Evidence for a sensitive period in the effects of early life stress on hippocampal volume"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5715-6597","authenticated-orcid":false,"given":"Kathryn L.","family":"Humphreys","sequence":"first","affiliation":[{"name":"Stanford University Stanford California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucy S.","family":"King","sequence":"additional","affiliation":[{"name":"Stanford University Stanford California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew D.","family":"Sacchet","sequence":"additional","affiliation":[{"name":"Stanford University Stanford California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0457-5410","authenticated-orcid":false,"given":"M. Catalina","family":"Camacho","sequence":"additional","affiliation":[{"name":"Stanford University Stanford California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7878-4250","authenticated-orcid":false,"given":"Natalie L.","family":"Colich","sequence":"additional","affiliation":[{"name":"Stanford University Stanford California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4148-8228","authenticated-orcid":false,"given":"Sarah J.","family":"Ordaz","sequence":"additional","affiliation":[{"name":"Stanford University Stanford California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiffany C.","family":"Ho","sequence":"additional","affiliation":[{"name":"Stanford University Stanford California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3622-3199","authenticated-orcid":false,"given":"Ian H.","family":"Gotlib","sequence":"additional","affiliation":[{"name":"Stanford University Stanford California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,12,26]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1300528"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1176\/jnp.2008.20.3.292"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.85.23.9331"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.21052"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhq137"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(96)00162-X"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2004.06.018"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-2028"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.112.1.155"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/15622975.2016.1208840"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.131.4.483"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.132.3.477"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-psych-010416-044224"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dcn.2017.12.005"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-7687.2008.00688.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.200033797"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(02)00569-X"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2016.11.010"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2010.01.006"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2015.07.008"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00787-009-0013-z"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn958"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2013.09.073"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.20193"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2014.04.020"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2014.10.020"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpp.12607"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2014.165"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1210\/edrv-12-2-118"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2009.02.010"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2006.03.004"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1101\/lm.037291.114"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2016.11.024"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1260497"},{"key":"e_1_2_6_36_1","unstructured":"Lee I. A. &Preacher K. J.(2013).Calculation for the test of the difference between two dependent correlations with one variable in common.http:\/\/doi.org\/http:\/\/quantpsy.org\/corrtest\/corrtest2.htm"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1118003109"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1601443113"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2006.09.041"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bandc.2007.02.007"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1105371108"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-psych-120710-100356"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1998.tb09546.x"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1177\/0963721416655883"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2014.10.012"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.2009.02084.x"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2008.12.033"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.4159\/harvard.9780674726079"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-08-0614"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2004.03.015"},{"key":"e_1_2_6_51_1","first-page":"386","article-title":"Psychometric review of traumatic event screening instrument for children (TESI\u2010C)","author":"Ribbe D.","year":"1996","journal-title":"Measurement of Stress, Trauma, and Adaptation"},{"key":"e_1_2_6_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/1467-8624.00048"},{"key":"e_1_2_6_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2005.01.066"},{"key":"e_1_2_6_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaac.2013.12.002"},{"key":"e_1_2_6_55_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1200041109"},{"key":"e_1_2_6_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2014.09.001"},{"key":"e_1_2_6_57_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.20573"},{"key":"e_1_2_6_58_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2011-2663"},{"key":"e_1_2_6_59_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291797005242"},{"key":"e_1_2_6_60_1","unstructured":"Suh J.W. Wang H. Das S. Avants B. &Yushkevich P.A.(2011).Automatic Segmentation of the Hippocampus in T1\u2010Weighted MRI with Multi\u2010Atlas Label Fusion Using Open Source Software: Evaluation in 1.5 and 3.0T ADNI MRI. In Proc Int Soc Magn Reson Med. Retrieved fromhttps:\/\/stage.nitrc.org\/docman\/view.php\/443\/912\/Abstract_JungSuh.pdf"},{"key":"e_1_2_6_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2008.01.004"},{"key":"e_1_2_6_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0149-7634(03)00007-1"},{"key":"e_1_2_6_63_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-7687.2009.00852.x"},{"key":"e_1_2_6_64_1","first-page":"68","article-title":"A review of adversity, the amygdala and the hippocampus: A consideration of developmental timing","volume":"3","author":"Tottenham N.","year":"2009","journal-title":"Frontiers in Human Neuroscience"},{"key":"e_1_2_6_65_1","unstructured":"U.S. Census Bureau. (2004).Current population survey: definitions and explanations. Retrieved fromhttp:\/\/www.census.gov\/population\/www\/cps\/cpsdef.html"},{"key":"e_1_2_6_66_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.20437"},{"key":"e_1_2_6_67_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpp.12642"},{"key":"e_1_2_6_68_1","volume-title":"DC:0\u20135: Diagnostic Classification of Mental Health and Developmental Disorders of Infancy and Early Childhood","author":"Zero to Three","year":"2016"},{"key":"e_1_2_6_69_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2017.00093"},{"key":"e_1_2_6_70_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0154530"}],"container-title":["Developmental Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fdesc.12775","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/desc.12775","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/desc.12775","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/am-pdf\/10.1111\/desc.12775","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/desc.12775","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T08:01:36Z","timestamp":1694246496000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/desc.12775"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,26]]},"references-count":69,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.1111\/desc.12775"],"URL":"https:\/\/doi.org\/10.1111\/desc.12775","archive":["Portico"],"relation":{},"ISSN":["1363-755X","1467-7687"],"issn-type":[{"value":"1363-755X","type":"print"},{"value":"1467-7687","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12,26]]},"assertion":[{"value":"2017-10-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e12775"}}