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Hyper\u2010connectivity of the intraparietal sulcus (IPS), a key locus of mathematical and numerical processing, has been associated with poor mathematical skills in childhood, whereas greater connectivity has been related to better performance in adulthood. No studies to date have considered its role in adolescence. Further, hippocampal connectivity can predict mathematical learning, yet no studies have considered its contributions to contemporaneous measures of math achievement. Here, we used seed\u2010based resting\u2010state fMRI analyses to examine IPS and hippocampal intrinsic functional connectivity relations to math achievement in a group of 31 adolescents (mean age\u00a0=\u00a016.42 years, range 15\u201317), whose math performance spanned the 1% to 99% percentile. After controlling for IQ, IPS connectivity was negatively related to math achievement, akin to findings in children. However, the specific temporo\u2010occipital regions were more akin to the posterior loci implicated in adults. Hippocampal connectivity with frontal regions was also negatively correlated with concurrent math measures, which contrasts with results from learning studies. Finally, hyper\u2010connectivity was not a global feature of low math performance, as math performance did not modulate connectivity of Heschl's gyrus, a control seed not involved in math cognition. Our results provide preliminary evidence that adolescence is a transitional stage in which patterns found in childhood and adulthood can be observed; most notably, hyper\u2010connectivity continues to be related to low math ability into this period.<\/jats:p>","DOI":"10.1111\/desc.13187","type":"journal-article","created":{"date-parts":[[2021,11,11]],"date-time":"2021-11-11T11:47:01Z","timestamp":1636631221000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Parietal and hippocampal hyper\u2010connectivity is associated with low math achievement in adolescence \u2013 A preliminary study"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6841-0917","authenticated-orcid":false,"given":"Roberto A.","family":"Abreu\u2010Mendoza","sequence":"first","affiliation":[{"name":"Department of Psychology Rutgers University\u2010Newark  Newark New Jersey 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M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Rosenberg\u2010Lee","sequence":"additional","affiliation":[{"name":"Department of Psychology Rutgers University\u2010Newark  Newark New Jersey USA"},{"name":"Center for Molecular and Behavioral Neuroscience Rutgers University\u2010Newark  Newark New Jersey 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