{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T10:21:48Z","timestamp":1789381308779,"version":"build-2803163510"},"reference-count":41,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2014,5,26]],"date-time":"2014-05-26T00:00:00Z","timestamp":1401062400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate the electroclinical features of epilepsy secondary to neonatal hypoglycaemia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This was a retrospective study of children who had seizures beyond infancy after neonatal hypoglycaemia treated at <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>he <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>oyal <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hildren's <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ospital, <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>elbourne between 1996 and 2012. Patients with perinatal asphyxia were excluded. Clinical details were obtained from medical records. Digital electroencephalography (<jats:styled-content style=\"fixed-case\">EEG<\/jats:styled-content>) and brain magnetic resonance imaging (<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>) were reviewed. Eleven patients met the inclusion criteria (six males, five females; mean age 10y 5mo, range 4\u201318y at the time of review).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Age at seizure onset ranged from 4\u00a0months to 5\u00a0years. Seizures were focal occipital in nine and generalized tonic in two patients. <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> showed gliosis with or without cortical atrophy in the occipital lobe with or without parietal lobe in all. Predominant <jats:styled-content style=\"fixed-case\">EEG<\/jats:styled-content> findings were stereotyped occipital sharp\u2010slow discharges in five, polymorphic occipital spike\u2010wave or paroxysmal fast activity in three, and generalized slow spike\u2010wave and fast activity in two. Seizures were infrequent or remitted in six of the nine children with focal occipital seizures, and frequent and refractory in both children with generalized seizures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interpretation<\/jats:title><jats:p>Despite the common antecedent and bilateral occipital lobe injury, the seizure manifestations and course of epilepsy after neonatal hypoglycaemia were variable, with mild occipital, refractory occipital, and symptomatic generalized epilepsy recognized.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dmcn.12496","type":"journal-article","created":{"date-parts":[[2014,5,26]],"date-time":"2014-05-26T06:52:55Z","timestamp":1401087175000},"page":"1093-1099","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Variable outcome for epilepsy after neonatal hypoglycaemia"],"prefix":"10.1111","volume":"56","author":[{"given":"Choong Yi","family":"Fong","sequence":"first","affiliation":[{"name":"Department of Neurology The Royal Children's Hospital Melbourne Melbourne Vic. 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