{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T15:47:42Z","timestamp":1777132062897,"version":"3.51.4"},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,9,23]],"date-time":"2014-09-23T00:00:00Z","timestamp":1411430400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"NIH-NICHD","award":["5R01HD059826"],"award-info":[{"award-number":["5R01HD059826"]}]},{"name":"National Institutes of Health - Eunice Kennedy Shriver National Institute of Child Health and Human Development"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate fat distribution in children and adolescents with myelomeningocele using dual\u2010energy X\u2010ray absorptiometry (<jats:styled-content style=\"fixed-case\">DXA<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Cross\u2010sectional <jats:styled-content style=\"fixed-case\">DXA<\/jats:styled-content> measurements of the percentage of fat in the trunk, arms, legs, and whole body were compared between 82 children with myelomeningocele (45 males, 37 females; mean age 9y 8mo, <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content> 2y 7mo; 22 sacral, 13 low lumbar, 47 mid lumbar and above) and 119 comparison children (65 males, 54 females; mean age 10y 4mo, <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content> 2y 4mo). Differences in fat distribution between groups were evaluated using univariate and multivariate analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Children with myelomeningocele had higher total body fat (34% vs 31%, <jats:italic>p<\/jats:italic>=0.02) and leg fat (42% vs 35%, <jats:italic>p<\/jats:italic>&lt;0.001) than comparison children, but no differences in trunk or arm fat after adjustment for anthropometric measures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interpretation<\/jats:title><jats:p>Children with myelomeningocele have higher than normal total body and leg fat, but only children with higher level lesions have increased trunk fat, which may be caused by greater obesity in this group. Quantifying segmental fat distribution may aid in better assessment of excess weight and, potentially, the associated health risks.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dmcn.12591","type":"journal-article","created":{"date-parts":[[2014,9,23]],"date-time":"2014-09-23T12:37:04Z","timestamp":1411475824000},"page":"273-278","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Fat distribution in children and adolescents with myelomeningocele"],"prefix":"10.1111","volume":"57","author":[{"given":"Nicole M","family":"Mueske","sequence":"first","affiliation":[{"name":"Children's Orthopaedic Center Children's Hospital Los Angeles Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deirdre D","family":"Ryan","sequence":"additional","affiliation":[{"name":"Children's Orthopaedic Center Children's Hospital Los Angeles Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander L","family":"Van Speybroeck","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Keck School of Medicine University of Southern California Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda S","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Keck School of Medicine University of Southern California Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tishya AL","family":"Wren","sequence":"additional","affiliation":[{"name":"Children's Orthopaedic Center Children's Hospital Los Angeles Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,9,23]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"1","article-title":"Finding balance obesity and children with special 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