{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T10:45:28Z","timestamp":1782125128803,"version":"3.54.5"},"reference-count":10,"publisher":"Wiley","issue":"S3","license":[{"start":{"date-parts":[[2015,3,19]],"date-time":"2015-03-19T00:00:00Z","timestamp":1426723200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:p>Infants who suffer hypoxic\u2013ischaemic encephalopathy (<jats:styled-content style=\"fixed-case\">HIE<\/jats:styled-content>) at term are at risk of dying or developing severe cerebral palsy (<jats:styled-content style=\"fixed-case\">CP<\/jats:styled-content>). Children with severe <jats:styled-content style=\"fixed-case\">CP<\/jats:styled-content> often have other neurodevelopmental disabilities, which may affect their quality of life as much as the <jats:styled-content style=\"fixed-case\">CP<\/jats:styled-content> itself. New treatments for <jats:styled-content style=\"fixed-case\">HIE<\/jats:styled-content>, such as cooling, may improve motor outcomes, but affected infants may still have significant cognitive or communication problems. Infants who have experienced <jats:styled-content style=\"fixed-case\">HIE<\/jats:styled-content> and develop <jats:styled-content style=\"fixed-case\">CP<\/jats:styled-content> will require significant medical input throughout childhood and adult life. The costs of this medical input are high, but the indirect costs to the child, his or her family, and the relevant social services and education systems are many times greater. When demonstrating the cost\u2010effectiveness of interventions aimed at preventing or treating <jats:styled-content style=\"fixed-case\">HIE<\/jats:styled-content>, these additional costs should be taken into account.<\/jats:p>","DOI":"10.1111\/dmcn.12727","type":"journal-article","created":{"date-parts":[[2015,3,20]],"date-time":"2015-03-20T16:23:52Z","timestamp":1426868632000},"page":"48-50","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":99,"title":["The long\u2010term health, social, and financial burden of hypoxic\u2013ischaemic encephalopathy"],"prefix":"10.1111","volume":"57","author":[{"given":"Paul","family":"Eunson","sequence":"first","affiliation":[{"name":"Department of Paediatric Neurosciences Royal Hospital for Sick Children Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,3,19]]},"reference":[{"key":"e_1_2_10_2_1","volume-title":"Neonatal Encephalopathy and Cerebral Palsy: Defining the Pathogenesis and Pathophysiology","author":"Task Force on Neonatal Encephalopathy and Cerebral Palsy Staff American College of Obstetricians and Gynecologists with American Academy of Pediatrics Staff","year":"2003"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2008.148205"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpn.2012.05.001"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(89)80132-5"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2004.067520"},{"key":"e_1_2_10_7_1","first-page":"57","article-title":"Economic costs associated with mental retardation, cerebral palsy, hearing loss and vision impairment \u2013 United States 2003","volume":"53","year":"2004","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2011.12.001"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2008.03190.x"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmr.2009.06.003"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2012.03.029"}],"container-title":["Developmental Medicine &amp; Child Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fdmcn.12727","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dmcn.12727","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T20:33:02Z","timestamp":1694637182000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/dmcn.12727"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,19]]},"references-count":10,"journal-issue":{"issue":"S3","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["10.1111\/dmcn.12727"],"URL":"https:\/\/doi.org\/10.1111\/dmcn.12727","archive":["Portico"],"relation":{},"ISSN":["0012-1622","1469-8749"],"issn-type":[{"value":"0012-1622","type":"print"},{"value":"1469-8749","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,19]]},"assertion":[{"value":"2014-09-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-03-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}