{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T18:18:27Z","timestamp":1771006707463,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,6,17]],"date-time":"2015-06-17T00:00:00Z","timestamp":1434499200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000053","name":"National Eye Institute","doi-asserted-by":"publisher","award":["U10 EY013287, U10 EY13272"],"award-info":[{"award-number":["U10 EY013287, U10 EY13272"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>To assess motor functioning in children aged 4\u00a0years 6\u00a0months enrolled in the Infant Aphakia Treatment Study, and to determine contributions of visual acuity and stereopsis to measured motor skills.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>One hundred and four children (53% female) with unilateral aphakia randomized to intraocular lens or contact lens treatment were evaluated at 4\u00a0years 6\u00a0months (age range 4y 6mo\u20134y 11mo) for monocular recognition visual acuity, motor skills, and stereopsis by a traveling examiner masked to treatment condition. Motor skills were assessed with the Movement Assessment Battery for Children \u2013 Second Edition (<jats:styled-content style=\"fixed-case\">MABC<\/jats:styled-content>\u20102). Visual acuity was operationalized as log<jats:sub>10<\/jats:sub> of the minimum angle of resolution (log<jats:styled-content style=\"fixed-case\">MAR<\/jats:styled-content>) value for treated eye, best log<jats:styled-content style=\"fixed-case\">MAR<\/jats:styled-content> value for either eye, and intraocular log<jats:styled-content style=\"fixed-case\">MAR<\/jats:styled-content> difference.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Student's <jats:italic>t<\/jats:italic>\u2010tests showed no significant differences in <jats:styled-content style=\"fixed-case\">MABC<\/jats:styled-content>\u20102 scores between the intraocular lens and contact lens groups. The mean total score was low (6.43; 18th centile) compared with the normative reference group. Motor functioning was not related to visual acuity in the treated eye or to intraocular log<jats:styled-content style=\"fixed-case\">MAR<\/jats:styled-content> difference, but was predicted in a regression model by the better visual acuity of either eye (usually the fellow eye), even after accounting for the influence of age at surgery, examiner, orthotropic ocular alignment, and stereopsis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interpretation<\/jats:title><jats:p>Children with unilateral congenital cataract may have delayed motor functioning at 4\u00a0years 6\u00a0months, which may adversely affect their social and academic functioning.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dmcn.12832","type":"journal-article","created":{"date-parts":[[2015,6,18]],"date-time":"2015-06-18T04:24:43Z","timestamp":1434601483000},"page":"154-159","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Motor skills of children with unilateral visual impairment in the Infant Aphakia Treatment Study"],"prefix":"10.1111","volume":"58","author":[{"given":"Marianne","family":"Celano","sequence":"first","affiliation":[{"name":"Emory University School of Medicine Atlanta GA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E Eugenie","family":"Hartmann","sequence":"additional","affiliation":[{"name":"Department of Vision Sciences University of Alabama Birmingham AL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lindreth G","family":"DuBois","sequence":"additional","affiliation":[{"name":"Emory University School of Medicine Atlanta GA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolyn","family":"Drews\u2010Botsch","sequence":"additional","affiliation":[{"name":"Rollins School of Public Health Emory University Atlanta GA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"the Infant Aphakia Treatment Study Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,6,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/09273972.2011.600423"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1076\/stra.10.3.187.8125"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.14-14745"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2006.090910"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.07-0869"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.10-6341"},{"key":"e_1_2_7_8_1","volume-title":"Movement Assessment Battery For Children\u20102: Examiner's Manual","author":"Henderson SE","year":"2007"},{"key":"e_1_2_7_9_1","first-page":"3687","article-title":"Outcome after very early treatment of dense congenital unilateral cataract","volume":"34","author":"Birch EE","year":"1993","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1091-8531(99)70080-7"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archophthalmol.2009.350"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2014.531"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(01)01256-9"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2011.01.035"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2011.01.032"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/archophthalmol.2010.101"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-2789"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.09-4434"},{"key":"e_1_2_7_19_1","first-page":"2080","article-title":"Development of grating acuity in children treated for unilateral or bilateral congenital cataract","volume":"36","author":"Lewis TL","year":"1995","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_7_20_1","doi-asserted-by":"crossref","first-page":"37","DOI":"10.3928\/0191-3913-19950101-09","article-title":"Reappraisal of occlusion therapy for severe structural abnormalities of the optic disc and macula","volume":"32","author":"Yang LL","year":"1994","journal-title":"J Pediatr Ophthalmol Strabismus"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/ACO.0000000000000016"},{"key":"e_1_2_7_22_1","first-page":"443","volume-title":"Developmental Motor Disorders: A Neuropsychological Perspective","author":"Larkin D","year":"2004"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-1056"}],"container-title":["Developmental Medicine &amp; 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