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The clinical picture of <jats:styled-content style=\"fixed-case\">CP<\/jats:styled-content> has changed with improved neonatal care over the past few decades, resulting in higher survival rates of infants born very preterm. Children born preterm seem particularly vulnerable to perinatal hypoxia\u2010ischemia insults at birth. Animal models of <jats:styled-content style=\"fixed-case\">CP<\/jats:styled-content> are crucial for elucidating underlying mechanisms and for development of strategies of neuroprotection and remediation. Most animal models of <jats:styled-content style=\"fixed-case\">CP<\/jats:styled-content> are based on hypoxia\u2010ischemia around the time of birth. In this review, we focus on alterations of brain organization and functions, especially sensorimotor changes, induced by prenatal ischemia in rodents and rabbits, and relate these alterations to neurodevelopmental disorders found in preterm children. We also discuss recent literature that addresses the relationship between neural and myelin plasticity, as well as possible contributions of white matter injury to the emergence of brain dysfunctions induced by prenatal ischemia.<\/jats:p>","DOI":"10.1111\/dmcn.13040","type":"journal-article","created":{"date-parts":[[2016,4,1]],"date-time":"2016-04-01T02:21:40Z","timestamp":1459477300000},"page":"7-11","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":55,"title":["Prenatal ischemia deteriorates white matter, brain organization, and function: implications for prematurity and cerebral palsy"],"prefix":"10.1111","volume":"58","author":[{"given":"Jacques\u2010Olivier","family":"Coq","sequence":"first","affiliation":[{"name":"Neurosciences Int\u00e9gratives et Adaptatives CNRS, Aix Marseille Universit\u00e9 Marseille France"},{"name":"Institut de Neurosciences de la Timone (INT) CNRS, Aix Marseille Universit\u00e9 Marseille 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