{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T14:25:01Z","timestamp":1782829501893,"version":"3.54.5"},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,6,4]],"date-time":"2016-06-04T00:00:00Z","timestamp":1464998400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1 TR000424"],"award-info":[{"award-number":["UL1 TR000424"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008771","name":"Tourette Association of America","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008771","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Primary complex motor stereotypies (<jats:styled-content style=\"fixed-case\">CMS<\/jats:styled-content>) are persistent, patterned, repetitive, rhythmic movements in young people with typical development. This study evaluated the efficacy of an instructional <jats:styled-content style=\"fixed-case\">DVD<\/jats:styled-content> as a home\u2010based, parent\u2010administered, behavioral therapy for primary <jats:styled-content style=\"fixed-case\">CMS<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Eighty\u2010one children with primary <jats:styled-content style=\"fixed-case\">CMS<\/jats:styled-content> were enrolled. Primary outcome measures included the Stereotypy Severity Scale (<jats:styled-content style=\"fixed-case\">SSS<\/jats:styled-content>) \u2013 Motor and Impairment scores, and Stereotypy Linear Analog Scale (<jats:styled-content style=\"fixed-case\">SLAS<\/jats:styled-content>). Mean <jats:styled-content style=\"fixed-case\">CMS<\/jats:styled-content> onset was 13.4 months (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content> 13.1). Eligibility required observed <jats:styled-content style=\"fixed-case\">CMS<\/jats:styled-content>. Psychiatric disorders were not exclusionary and a stable medication regimen was required. Intellectual disability, neurological disorder, autism spectrum disorder, and tics were exclusionary. Initial assessments were completed via <jats:styled-content style=\"fixed-case\">REDC<\/jats:styled-content>ap before receipt of the <jats:styled-content style=\"fixed-case\">DVD<\/jats:styled-content>. Fifty\u2010four of the 81 children (34 male, 20 female; mean age 8y 2mo, <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content> 1.42, range 7\u201314y) completed assessments at 1, 2, or 3 months after receiving the <jats:styled-content style=\"fixed-case\">DVD<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Reductions (baseline to last assessment) in <jats:styled-content style=\"fixed-case\">SSS<\/jats:styled-content> Motor, <jats:styled-content style=\"fixed-case\">SSS<\/jats:styled-content> Impairment, and <jats:styled-content style=\"fixed-case\">SLAS<\/jats:styled-content> scores (all <jats:italic>p<\/jats:italic>&lt;0.001) represented change ratios of \u221215%, \u221224%, and a \u221220% respectively. Greatest relative treatment benefit was observed by younger children (ages 7\u20138y), and by 1 month after receipt of <jats:styled-content style=\"fixed-case\">DVD<\/jats:styled-content>, while a parent global assessment scale showed progressive improvement throughout the study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interpretation<\/jats:title><jats:p>An instructional <jats:styled-content style=\"fixed-case\">DVD<\/jats:styled-content> for parent\u2010delivered behavioral therapy was a safe, effective intervention for primary <jats:styled-content style=\"fixed-case\">CMS<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dmcn.13164","type":"journal-article","created":{"date-parts":[[2016,6,4]],"date-time":"2016-06-04T06:58:50Z","timestamp":1465023530000},"page":"168-173","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Efficacy of parent\u2010delivered behavioral therapy for primary complex motor stereotypies"],"prefix":"10.1111","volume":"59","author":[{"given":"Matthew W","family":"Specht","sequence":"first","affiliation":[{"name":"Johns Hopkins University School of Medicine Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E Mark","family":"Mahone","sequence":"additional","affiliation":[{"name":"Johns Hopkins University School of Medicine Baltimore MD USA"},{"name":"Kennedy Krieger Institute Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tina","family":"Kline","sequence":"additional","affiliation":[{"name":"Johns Hopkins University School of Medicine Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Waranch","sequence":"additional","affiliation":[{"name":"Johns Hopkins University School of Medicine Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurel","family":"Brabson","sequence":"additional","affiliation":[{"name":"Johns Hopkins University School of Medicine Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carol B","family":"Thompson","sequence":"additional","affiliation":[{"name":"Johns Hopkins Bloomberg School of Public Health Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harvey S","family":"Singer","sequence":"additional","affiliation":[{"name":"Johns Hopkins University School of Medicine Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,6,4]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0b013e328307bf1c"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2004.06.014"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199807000-00010"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2014.11.002"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870120109"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/08830738060210020701"},{"key":"e_1_2_7_8_1","unstructured":"HofferTB DugoniBL SandersonAR et al.Doctorate recipients from United States universities: summary report 2000. 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