{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T14:49:28Z","timestamp":1789138168503,"version":"build-2803163510"},"reference-count":56,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2017,6,19]],"date-time":"2017-06-19T00:00:00Z","timestamp":1497830400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To compare the oral health status of children and adolescents affected by intellectual disabilities with their unaffected counterparts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>\n                      Citations published in English were searched from electronic databases (PubMed, Embase, Web of Science, and Scopus) from their start dates to March 2017. The whole process was conducted following\n                      <jats:styled-content style=\"fixed-case\">PRISMA<\/jats:styled-content>\n                      (Preferred Reporting Items for Systematic reviews and Meta\u2010Analyses) guidelines. The\n                      <jats:styled-content style=\"fixed-case\">PICO<\/jats:styled-content>\n                      (population, intervention\/interest, comparator, outcome) principle was used to formulate the topic. Studies were synthesized through qualitative summary or, whenever possible, meta\u2010analysis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The initial search yielded 2393 records. Thirty\u2010nine studies from 22 countries were identified for qualitative analysis; 26 studies were eligible for meta\u2010analysis. Participants with intellectual disabilities had higher levels of dental plaque, worse gingival status, fewer decayed and filled permanent teeth, and similar caries experience between males and females. These findings were supported by both qualitative and quantitative analysis. Various patterns of caries experiences were indicated by qualitative analysis, but it was not substantiated by meta\u2010analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interpretation<\/jats:title>\n                    <jats:p>There is increasing worldwide interest in oral health status of children with intellectual disabilities. Differences in dental plaque deposition, gingival inflammation, and the number of decayed and filled permanent teeth were investigated between children and adolescents with and without intellectual disabilities. Evidence remains elusive about the pattern of caries experience among those children.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dmcn.13486","type":"journal-article","created":{"date-parts":[[2017,6,19]],"date-time":"2017-06-19T01:32:48Z","timestamp":1497835968000},"page":"1019-1026","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":78,"title":["Oral health status of children and adolescents with intellectual disabilities: a systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"59","author":[{"given":"Ni","family":"Zhou","sequence":"first","affiliation":[{"name":"Department of Paediatric Dentistry and Orthodontics Faculty of Dentistry The University of Hong Kong Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3411-6442","authenticated-orcid":false,"given":"Hai Ming","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Paediatric Dentistry and Orthodontics Faculty of Dentistry The University of Hong Kong Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi Feng","family":"Wen","sequence":"additional","affiliation":[{"name":"Department of Paediatric Dentistry and Orthodontics Faculty of Dentistry The University of Hong Kong Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colman","family":"Mcgrath","sequence":"additional","affiliation":[{"name":"Department of Periodontology and Public Health Faculty of Dentistry The University of Hong Kong Hong Kong SAR"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,6,19]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"American Association on Intellectual and Developmental Disabilities.Diagnostic Adaptive Behavior Scale. Available at:https:\/\/aaidd.org\/intellectual-disability\/diagnostic-adaptive-behavior-scale.WQqdqxOGOM8(accessed 4 May 2017)."},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.17796\/1053-4628-40.1.21"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ipd.12067"},{"key":"e_1_2_7_5_1","first-page":"27","article-title":"Prevalence of periodontal disease in the primary dentition of children with cerebral palsy","volume":"71","author":"Guare RO","year":"2004","journal-title":"J Dent Child"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1678-77572011000300006"},{"key":"e_1_2_7_7_1","first-page":"37","article-title":"Some factors associated with dental caries in the primary dentition of children with Down syndrome","volume":"12","author":"Mathias MF","year":"2011","journal-title":"Eur J Paediatr Dent"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-263X.2010.01062.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-4388.130967"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.4103\/0972-124X.145800"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1754-4505.2002.tb01171.x"},{"key":"e_1_2_7_12_1","first-page":"63","article-title":"Oral health status of teenagers and young adults with intellectual impairment in Athens, Greece","volume":"9","author":"Kavvadia K","year":"2008","journal-title":"J Disabil Oral Health"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/scd.12015"},{"key":"e_1_2_7_14_1","first-page":"CD010625","article-title":"Clozapine for psychotic disorders in adults with intellectual disabilities","volume":"9","author":"Ayub M","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.2004.00150.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/eos.12150"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/1362361314553439"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-263X.2010.01045.x"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.2004.00457.x"},{"key":"e_1_2_7_20_1","unstructured":"World Health Organization.Handbook for Guideline Development.2012. Available at:http:\/\/apps.who.int\/iris\/bitstream\/10665\/75146\/1\/9789241548441_eng.pdf?ua=1(accessed 22 February 2017)."},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.092252"},{"key":"e_1_2_7_22_1","first-page":"CD003864","article-title":"Staff\u2010led interventions for improving oral hygiene in patients following stroke","volume":"4","author":"Brady M","year":"2006","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.3945\/an.114.006395"},{"key":"e_1_2_7_24_1","first-page":"CD003406","article-title":"Behavioural and cognitive\u2010behavioural interventions for outwardly\u2010directed aggressive behaviour in people with intellectual disabilities","volume":"4","author":"Ali A","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/jir.12111"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2010.02.007"},{"key":"e_1_2_7_27_1","unstructured":"WellsG SheaB O'ConnellD et\u00a0al.The Newcastle\u2010Ottawa Scale (NOS) for Assessing the Quality of Nonrandomised Studies in Meta\u2010analyses. Available at:http:\/\/www.medicine.mcgill.ca\/rtamblyn\/Readings%5CThe%20Newcastle%20-%20Scale%20for%20assessing%20the%20quality%20of%20nonrandomised%20studies%20in%20meta-analyses.pdf(accessed 30\u00a0October 2016)."},{"key":"e_1_2_7_28_1","first-page":"219","article-title":"The status of oral health in cerebral palsy children and their siblings","volume":"34","author":"Fishman SR","year":"1967","journal-title":"J Dent Child"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.1982.tb00369.x"},{"key":"e_1_2_7_30_1","first-page":"156","article-title":"The dental status of cerebral palsied children","volume":"13","author":"Pope JE","year":"1991","journal-title":"Pediatr Dent"},{"key":"e_1_2_7_31_1","first-page":"19","article-title":"Oral hygiene status of mentally handicapped school children in Ibadan, Nigeria","volume":"21","author":"Denloye OO","year":"1998","journal-title":"Odontostomatol Trop"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2005.06.001"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1754-4505.2006.tb01504.x"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-5037.2012.00545.x"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.4103\/0972-124X.100923"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2012.03.006"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/scd.12054"},{"key":"e_1_2_7_38_1","first-page":"ZC110","article-title":"Comparison of gingival health and salivary parameters among autistic and non\u2010autistic school children in Riyadh","volume":"10","author":"Diab HM","year":"2016","journal-title":"J Clin Diagn Res"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.17796\/1053-4628-40.5.375"},{"key":"e_1_2_7_40_1","first-page":"15","article-title":"Dental health and dental care in severely mentally retarded children","volume":"9","author":"Forsberg H","year":"1985","journal-title":"Swed Dent J"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1754-4505.1991.tb01732.x"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1997.68.7.626"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2000.71.2.249"},{"key":"e_1_2_7_44_1","first-page":"256","article-title":"Periodontal status and orthodontic treatment need of autistic children","volume":"11","author":"Luppanapornlarp S","year":"2010","journal-title":"World J Orthod"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40368-014-0156-6"},{"key":"e_1_2_7_46_1","first-page":"267","article-title":"Caries among children with cerebral palsy: relation to CP\u2010diagnosis, mental and motor handicap","volume":"57","author":"Nielsen LA","year":"1990","journal-title":"ASDC J Dent Child"},{"key":"e_1_2_7_47_1","first-page":"287","article-title":"Dental caries prevalence in the primary dentition of cerebral\u2010palsied children","volume":"27","author":"Guare RO","year":"2003","journal-title":"J Clin Pediatr Dent"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.17796\/jcpd.36.3.d716250117827056"},{"key":"e_1_2_7_49_1","first-page":"23","article-title":"Does the chemistry in the saliva of Down syndrome children explain their low caries prevalence?","volume":"14","author":"Areias C","year":"2013","journal-title":"Eur J Paediatr Dent"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sdentj.2015.03.003"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-4388.33457"},{"key":"e_1_2_7_52_1","first-page":"761","article-title":"Dental health and dental care in children with cerebral palsy","volume":"35","author":"Grzic R","year":"2011","journal-title":"Coll Antropol"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2012.03.026"},{"key":"e_1_2_7_54_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40368-016-0231-2"},{"key":"e_1_2_7_55_1","doi-asserted-by":"publisher","DOI":"10.1111\/scd.12191"},{"key":"e_1_2_7_56_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199708213370810"},{"key":"e_1_2_7_57_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a117326"}],"container-title":["Developmental Medicine &amp; Child Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fdmcn.13486","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dmcn.13486","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/dmcn.13486","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dmcn.13486","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T08:19:58Z","timestamp":1694765998000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/dmcn.13486"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,19]]},"references-count":56,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["10.1111\/dmcn.13486"],"URL":"https:\/\/doi.org\/10.1111\/dmcn.13486","archive":["Portico"],"relation":{},"ISSN":["0012-1622","1469-8749"],"issn-type":[{"value":"0012-1622","type":"print"},{"value":"1469-8749","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,19]]},"assertion":[{"value":"2017-04-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-06-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}