{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T16:49:19Z","timestamp":1792514959313,"version":"4.5.0"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,8,21]],"date-time":"2018-08-21T00:00:00Z","timestamp":1534809600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100006741","name":"Stiftelsen Frimurare Barnhuset i Stockholm","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006741","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008588","name":"Stiftelsen Sunnerdahls Handikappfond","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008588","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To evaluate neurodevelopmental difficulties in children with idiopathic clubfoot.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>\n                      A cross\u2010sectional study of 106 children (29 females, 77 males; aged 8\u201310y) with idiopathic clubfoot and 109 age\u2010, sex\u2010, and residential area\u2010parallelized children from the general population. Neurodevelopmental difficulties were assessed using the parent\u2010report Five to Fifteen (\n                      <jats:styled-content style=\"fixed-case\">FTF<\/jats:styled-content>\n                      ) questionnaire. Group differences were analysed for\n                      <jats:styled-content style=\"fixed-case\">FTF<\/jats:styled-content>\n                      domains, subdomains, and items. The 90th centile cut\u2010off of the general population on\n                      <jats:styled-content style=\"fixed-case\">FTF<\/jats:styled-content>\n                      and the parent\u2010based disease\u2010specific instrument (\n                      <jats:styled-content style=\"fixed-case\">DSI<\/jats:styled-content>\n                      ) were used to evaluate clinical relevance of neurodevelopmental symptoms in idiopathic clubfoot.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Modest group differences were found for several\n                      <jats:styled-content style=\"fixed-case\">FTF<\/jats:styled-content>\n                      domains (motor skills, perception, and language) and subdomains (gross and fine motor skills, relation in space, comprehensive and expressive language skills). Thirty\u2010one per cent of the children with idiopathic clubfoot scored in the clinically significant range on 2 or more\n                      <jats:styled-content style=\"fixed-case\">FTF<\/jats:styled-content>\n                      domains.\n                      <jats:styled-content style=\"fixed-case\">DSI<\/jats:styled-content>\n                      scores were lower in this subgroup.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interpretation<\/jats:title>\n                    <jats:p>Findings indicate a moderate and selective increase of neurodevelopmental difficulties in children with idiopathic clubfoot as a whole, especially in the areas of motor skills, perception, and language. Idiopathic clubfoot with marked neurodevelopmental symptoms are associated with less satisfaction of the clubfoot treatment. Our results recommend awareness of neurodevelopmental difficulties in the assessment and treatment of idiopathic clubfoot.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>What this paper adds<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>A substantial minority of children with idiopathic clubfoot show neurodevelopmental difficulties.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Children with idiopathic clubfoot might present additional difficulties in motor skills, perception, and language.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Children with idiopathic clubfoot and marked neurodevelopmental symptoms show poorer parent\u2010reported clubfoot treatment satisfaction.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Neurodevelopmental difficulties should be considered in clinical practice of idiopathic clubfoot.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dmcn.13996","type":"journal-article","created":{"date-parts":[[2018,8,22]],"date-time":"2018-08-22T11:55:54Z","timestamp":1534938954000},"page":"98-104","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Neurodevelopmental difficulties in children with idiopathic clubfoot"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2747-3046","authenticated-orcid":false,"given":"Elin","family":"L\u00f6\u00f6f","sequence":"first","affiliation":[{"name":"Division of Neurology\/Orthopedics\/Reumatology Department of Women's and Children's Health Karolinska Institutet Karolinska University Hospital Stockholm Sweden"},{"name":"Functional Area Occupational Therapy &amp; Physiotherapy Allied Health Professionals Function Karolinska University Hospital Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6938-8451","authenticated-orcid":false,"given":"Hanneke","family":"Andriesse","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Sk\u00e5nes University Hospital Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2967-8080","authenticated-orcid":false,"given":"Eva W","family":"Brostr\u00f6m","sequence":"additional","affiliation":[{"name":"Division of Neurology\/Orthopedics\/Reumatology Department of Women's and Children's Health Karolinska Institutet Karolinska University Hospital Stockholm Sweden"},{"name":"Pediatric Neurology and Musculoskeletal Disorders and Home Care Astrid Lindgren Children's Hospital Karolinska University Hospital Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8194-8236","authenticated-orcid":false,"given":"Marie","family":"Andr\u00e9","sequence":"additional","affiliation":[{"name":"Functional Area Occupational Therapy &amp; Physiotherapy Allied Health Professionals Function Karolinska University Hospital Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4579-4970","authenticated-orcid":false,"given":"Sven","family":"B\u00f6lte","sequence":"additional","affiliation":[{"name":"Center of Neurodevelopmental Disorders at Karolinska Institutet (KIND) Division of Neuropsychiatry Department of Women's and Children's Health Karolinska Institutet Stockholm Sweden"},{"name":"Child and Adolescent Psychiatry Center for Psychiatry Research Stockholm County Council Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,8,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-009-0734-9"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmg.2014.06.001"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/17453670610013123"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2008.03016.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.G.01346"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ppe.12163"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.35955"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0000000000000157"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-013-2031-1"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-201008000-00005"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1355617703960012"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2431-9-78"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/BPO.0000000000000964"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/BPO.0b013e31826bec08"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/0883073810385344"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpp.12645"},{"key":"e_1_2_7_18_1","unstructured":"Statistics Sweden.Official Statistics of Sweden. 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