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Optic chiasm thickness correlated negatively in patients with <jats:styled-content style=\"fixed-case\">WFS<\/jats:styled-content> with both age (<jats:italic>r<\/jats:italic>=\u22120.79; <jats:italic>p<\/jats:italic>=0.002) and duration of diabetes (<jats:italic>r<\/jats:italic>=\u22120.62; <jats:italic>p<\/jats:italic>=0.032). Thickness of the intraorbital parts of the optic nerves in patients with <jats:styled-content style=\"fixed-case\">WFS<\/jats:styled-content> correlated positively with thickness of the superior <jats:styled-content style=\"fixed-case\">RNFL<\/jats:styled-content> (<jats:italic>r<\/jats:italic>=0.73; <jats:italic>p<\/jats:italic>=0.006).<\/jats:p><\/jats:sec><jats:sec><jats:title>Interpretation<\/jats:title><jats:p>High\u2010definition OCT in combination with MRI could become an important tool for evaluating the effectiveness of therapeutic trials in patients with WFS.<\/jats:p><\/jats:sec><jats:sec><jats:title>What this paper adds<\/jats:title><jats:p>\n<jats:list list-type=\"bullet\">\n\n<jats:list-item><jats:p>Provides evidence of significant reduction of retinal parameters and optic nerves in patients with Wolfram syndrome (WFS).<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>Shows correlations between magnetic resonance imaging parameters and retinal morphology parameters in patients with WFS.<\/jats:p><\/jats:list-item>\n<\/jats:list>\n<\/jats:p><\/jats:sec>","DOI":"10.1111\/dmcn.14040","type":"journal-article","created":{"date-parts":[[2018,9,24]],"date-time":"2018-09-24T06:45:28Z","timestamp":1537771528000},"page":"359-365","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Optical coherence tomography and magnetic resonance imaging visual pathway evaluation in Wolfram syndrome"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8781-4469","authenticated-orcid":false,"given":"Agnieszka","family":"Zmyslowska","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Oncology, Hematology and Diabetology Medical University of \u0141\u00f3d\u017a \u0141\u00f3d\u017a Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arleta","family":"Waszczykowska","sequence":"additional","affiliation":[{"name":"Department of 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