{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T20:24:50Z","timestamp":1792182290359,"version":"4.4.0"},"reference-count":21,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,11,12]],"date-time":"2019-11-12T00:00:00Z","timestamp":1573516800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>To describe the long\u2010term outcomes of children by the time they reached school age with vein of Galen aneurysmal malformation (VGAM).<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This was a retrospective observational study on a consecutive cohort of patients with VGAM. We included patients with at least one Francophone parent, aged between 6 and 11 years at the time of long\u2010term evaluation. The neurological outcome was assessed with the King\u2019s Outcome Scale for Childhood Injury score and eight neurological and behavioural items from the Rivermead Postconcussion Symptoms questionnaire.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All 52 patients (17 females, 32 males [data missing for <jats:italic>n<\/jats:italic>=3]) with at least one Francophone parent (5 fetuses and 47 children) were included. At the long\u2010term evaluation time\u2010point, 33 patients were alive and 19 patients had died. Risk of postnatal death was associated with severe neonatal cardiac failure (<jats:italic>p<\/jats:italic>=0.007) or isosystemic or suprasystemic pulmonary hypertension (<jats:italic>p<\/jats:italic>=0.014). Among survivors, 19 had a good outcome with normal schooling and 14 had a poor outcome. Moreover, among the good outcome patients, a large proportion had neurodevelopmental alterations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interpretation<\/jats:title><jats:p>Long\u2010term outcome of patients with VGAM appears to be less favourable than outcome described at the short\u2010 and medium\u2010term, even in the absence of encephalomalacia at birth. Even patients with good outcome often have neuropsychological disorders that may have repercussions on learning and requiring appropriate rehabilitation or medical management.<\/jats:p><\/jats:sec><jats:sec><jats:title>What this paper adds<\/jats:title><jats:p>\n<jats:list list-type=\"bullet\">\n\n<jats:list-item><jats:p>Long\u2010term outcome appears to be less favourable than described at short\u2010 and medium\u2010term follow\u2010up.<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>Even patients with good outcome at these time\u2010points often have minor neuropsychological disorders.<\/jats:p><\/jats:list-item>\n<\/jats:list>\n<\/jats:p><\/jats:sec>","DOI":"10.1111\/dmcn.14392","type":"journal-article","created":{"date-parts":[[2019,11,12]],"date-time":"2019-11-12T12:41:52Z","timestamp":1573562512000},"page":"729-734","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Long\u2010term outcome of vein of Galen malformation"],"prefix":"10.1111","volume":"62","author":[{"given":"H\u00e9l\u00e8ne","family":"Taffin","sequence":"first","affiliation":[{"name":"Neurologie P\u00e9diatrique H\u00f4pital Bic\u00eatre Le Kremlin Bic\u00eatre France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9l\u00e8ne","family":"Maurey","sequence":"additional","affiliation":[{"name":"Neurologie P\u00e9diatrique H\u00f4pital Bic\u00eatre Le Kremlin Bic\u00eatre France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Augustin","family":"Ozanne","sequence":"additional","affiliation":[{"name":"Neuroradiologie H\u00f4pital Bic\u00eatre Le Kremlin Bic\u00eatre France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Durand","sequence":"additional","affiliation":[{"name":"R\u00e9animation P\u00e9diatrique H\u00f4pital Bic\u00eatre Le Kremlin Bic\u00eatre 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P\u00e9diatrique H\u00f4pital Bic\u00eatre Le Kremlin Bic\u00eatre France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3832-7976","authenticated-orcid":false,"given":"Guillaume","family":"Saliou","sequence":"additional","affiliation":[{"name":"Neuroradiologie H\u00f4pital Bic\u00eatre Le Kremlin Bic\u00eatre France"},{"name":"Radiodiagnostic et Radiologie Interventionnelle Centre Hospitalier et Universitaire Vaudois (CHUV) Lausanne Switzerland"},{"name":"Facult\u00e9 de Biologie et de M\u00e9decine UNIL Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,11,12]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"117","volume-title":"Surgical neuroangiography: vol. 3: clinical and interventional aspects in children","author":"Lasjaunias P","year":"2007"},{"issue":"3","key":"e_1_2_8_3_1","first-page":"S184","article-title":"The management of vein of Galen 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