{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T16:22:08Z","timestamp":1791044528625,"version":"4.1.0"},"reference-count":16,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,1,3]],"date-time":"2020-01-03T00:00:00Z","timestamp":1578009600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:sec><jats:label\/><jats:p>Endovascular clot retrieval (ECR) is an emerging therapy for treatment of acute ischaemic stroke (AIS) in adults, including basilar artery occlusion (BAO). Its role in children is not well established. We report four consecutive children with AIS due to BAO treated with ECR in Sydney, Australia. We reviewed the literature to characterize the \u2018natural course\u2019 of AIS due to BAO in children not treated with thrombolysis or ECR, and compared their outcome with our patients and reported children with BAO treated with ECR. Despite delays in diagnosis, ECR achieved recanalization in our four children. Three children had a good outcome (Paediatric Modified Rankin Score [PedmRS] 0\u20132). One child with acute leukaemia suffered recurrent basilar occlusion and died of brainstem dysfunction. Literature review identified 111 children exhibiting the natural course of AIS due to BAO, among whom 42% had good outcomes (PedmRS 0\u20132), 48% had significant residual disability (PedmRS 3\u20135), and 10% died. Of 34 children treated with ECR, 28 (82%) had good outcomes (PedmRS 0\u20132), five (15%) had significant residual disability (PedmRS 3\u20135), and one (3%) died. Complications of ECR were uncommon. These observations suggest ECR may be beneficial for children with AIS due to BAO.<\/jats:p><\/jats:sec><jats:sec><jats:title>What this paper adds<\/jats:title><jats:p>\n<jats:list list-type=\"bullet\">\n\n<jats:list-item><jats:p>Children with acute ischaemic stroke (AIS) due to basilar artery occlusion (BAO) experience significant morbidity and mortality.<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>Endovascular clot retrieval may be beneficial in children with AIS due to BAO.<\/jats:p><\/jats:list-item>\n<\/jats:list>\n<\/jats:p><\/jats:sec>","DOI":"10.1111\/dmcn.14449","type":"journal-article","created":{"date-parts":[[2020,1,3]],"date-time":"2020-01-03T09:17:58Z","timestamp":1578043078000},"page":"1221-1223","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Endovascular clot retrieval for acute ischaemic stroke due to basilar artery occlusion in childhood"],"prefix":"10.1111","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9894-4610","authenticated-orcid":false,"given":"Emma","family":"Macdonald\u2010Laurs","sequence":"first","affiliation":[{"name":"Department of Neurology Sydney Children\u2019s Hospital Randwick Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Wenderoth","sequence":"additional","affiliation":[{"name":"Department of Neurointervention Prince of Wales Hospital Sydney Australia"},{"name":"Faculty of Medicine University of New South Wales Kensington Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Cardamone","sequence":"additional","affiliation":[{"name":"Department of Neurology Sydney Children\u2019s Hospital Randwick Australia"},{"name":"Faculty of Medicine University of New South Wales Kensington Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo","family":"Sampaio","sequence":"additional","affiliation":[{"name":"Department of Neurology Sydney Children\u2019s Hospital Randwick Australia"},{"name":"Faculty of Medicine University of New South Wales Kensington Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P Ian","family":"Andrews","sequence":"additional","affiliation":[{"name":"Department of Neurology Sydney Children\u2019s Hospital Randwick Australia"},{"name":"Faculty of Medicine University of New South Wales Kensington Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,1,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(11)70229-0"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70173-5"},{"key":"e_1_2_8_4_1","first-page":"545","article-title":"Occlusion of the basilar artery. A review of 17 personal cases","volume":"137","author":"Labauge R","year":"1981","journal-title":"Rev Neurol (Paris)"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.12092"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.12051"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.12015"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000158"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.118.023361"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/ene.13809"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.18042.1"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2018.04.022"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2011-010100"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.2010.01974.x"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1706442"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/1747493018799958"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11940-015-0349-2"}],"container-title":["Developmental Medicine &amp; Child Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fdmcn.14449","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dmcn.14449","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/dmcn.14449","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dmcn.14449","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T01:40:28Z","timestamp":1693705228000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/dmcn.14449"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,3]]},"references-count":16,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["10.1111\/dmcn.14449"],"URL":"https:\/\/doi.org\/10.1111\/dmcn.14449","archive":["Portico"],"relation":{},"ISSN":["0012-1622","1469-8749"],"issn-type":[{"value":"0012-1622","type":"print"},{"value":"1469-8749","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,3]]},"assertion":[{"value":"2019-11-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}