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Study quality was evaluated and significant intervention effects and effect sizes were extracted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010eight articles were identified. They covered seven different interventions including stretching, botulinum neurotoxin A (BoNT\u2010A), strengthening, electrical stimulation, whole\u2010body vibration, balance training, and orthopaedic surgery. Study quality ranged from poor (14 out of 28 studies) to good (2 out of 28). Study samples were small (<jats:italic>n<\/jats:italic>=4\u201332) and studies were variable regarding which muscles and macroscopic morphological parameters were assessed. Inconsistent effects after intervention (thickness and cross\u2010sectional area for strengthening, volume for BoNT\u2010A), no effect (belly length for stretching), and small effect sizes were reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interpretation<\/jats:title><jats:p>Intervention studies reporting macroscopic muscle\u2013tendon remodelling after interventions are limited and heterogeneous, making it difficult to generalize results. Studies that include control groups and standardized assessment protocols are needed to improve study quality and data synthesis. Lack or inconclusive effects at the macroscopic level could indicate that the effects of interventions should also be evaluated at the microscopic level.<\/jats:p><\/jats:sec><jats:sec><jats:title>What this paper adds<\/jats:title><jats:p>\n<jats:list list-type=\"bullet\">\n\n<jats:list-item><jats:p>Muscle\u2010targeted interventions to remodel muscle morphology are not well understood.<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>Studies reporting macroscopic muscle remodelling following interventions are limited and heterogeneous.<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>Passive stretching may preserve but does not increase muscle length.<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>The effects of isolated botulinum neurotoxin A injections on muscle volume are inconsistent.<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>Isolated strengthening shows no consistent increase in muscle volume or thickness.<\/jats:p><\/jats:list-item>\n<\/jats:list>\n<\/jats:p><\/jats:sec>","DOI":"10.1111\/dmcn.14652","type":"journal-article","created":{"date-parts":[[2020,9,2]],"date-time":"2020-09-02T13:40:46Z","timestamp":1599054046000},"page":"274-286","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Interventions and lower\u2010limb macroscopic muscle morphology in children with spastic cerebral palsy: a scoping review"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3487-3689","authenticated-orcid":false,"given":"Fenna","family":"Walhain","sequence":"first","affiliation":[{"name":"Department of Anatomy Anton de Kom University of Suriname Paramaribo Suriname"},{"name":"Department of Rehabilitation Sciences Katholieke Universiteit Leuven Leuven 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