{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T22:13:58Z","timestamp":1790201638019,"version":"4.1.0"},"reference-count":37,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T00:00:00Z","timestamp":1648857600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100009157","name":"National Institute on Disability, Independent Living, and Rehabilitation Research","doi-asserted-by":"publisher","award":["90IF0055\u201001"],"award-info":[{"award-number":["90IF0055\u201001"]}],"id":[{"id":"10.13039\/100009157","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009157","name":"National Institute on Disability, Independent Living, and Rehabilitation Research","doi-asserted-by":"publisher","award":["H133G130200"],"award-info":[{"award-number":["H133G130200"]}],"id":[{"id":"10.13039\/100009157","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>To examine the relationship between quantitative gait measurements and self\u2010reported physical, psychological, cognitive, and social function status in young adults with cerebral palsy (CP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Seventy\u2010two adults with CP (range 18\u201348y; median age 23y [interquartile range 21\u201327y]; 34 males, 38 females), in Gross Motor Function Classification System levels I to IV, who previously underwent an instrumented gait analysis (IGA) at our center as children were recruited. Participants underwent a repeated IGA. National Institutes of Health Patient\u2010Reported Outcomes Information System (PROMIS) instruments including the PROMIS\u201057, Applied Cognition \u2013 General Concerns (Short Form), and Applied Cognition \u2013 Executive Function (Short Form) were administered. Data derived from current and prior IGA were compared via non\u2010parametric correlation analysis with PROMIS subscores.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Subscores for anxiety, depression, sleep, and fatigue did not significantly correlate with any IGA data. Walking speed, adjusted for stature, correlated strongly with multiple subscores: physical function (<jats:italic>p<\/jats:italic>&lt;0.001, <jats:italic>r<\/jats:italic><jats:sub><jats:italic>s<\/jats:italic><\/jats:sub>=0.708); participation in social roles (<jats:italic>p<\/jats:italic>=0.007, <jats:italic>r<\/jats:italic><jats:sub><jats:italic>s<\/jats:italic><\/jats:sub>=0.319); executive function (<jats:italic>p<\/jats:italic>=0.005, <jats:italic>r<\/jats:italic><jats:sub><jats:italic>s<\/jats:italic><\/jats:sub>=0.335). Pain interference correlated with longitudinal change in adjusted walking speed (<jats:italic>p<\/jats:italic>=0.032, <jats:italic>r<\/jats:italic><jats:sub><jats:italic>s<\/jats:italic><\/jats:sub>=\u20130.259). The Applied Cognition \u2013 General Concerns (Short Form) correlated with prior absolute walking speed, but not adjusted values.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interpretation<\/jats:title><jats:p>This study underscores the importance of walking speed and its association with a variety of functional domains in adults with CP.<\/jats:p><\/jats:sec><jats:sec><jats:title>What this paper adds<\/jats:title><jats:p>\n<jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>Patient\u2010Reported Outcomes Information System measures provide useful clinical data in young adults with cerebral palsy.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Temporospatial gait parameters have wide\u2010reaching functional influence in this population.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Walking speed is strongly correlated with physical, social, and executive function.<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p><\/jats:sec>","DOI":"10.1111\/dmcn.15225","type":"journal-article","created":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T14:23:28Z","timestamp":1648909408000},"page":"1281-1288","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Walking speed and patient\u2010reported outcomes in young adults with cerebral palsy"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2291-6699","authenticated-orcid":false,"given":"Matthew","family":"MacCarthy","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation University of Pittsburgh and UPMC Children\u2019s Hospital of Pittsburgh  Pittsburgh PA USA"},{"name":"Department of Pediatrics University of South Carolina and Prisma Health Children\u2019s Hospital  Columbia SC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Heyn","sequence":"additional","affiliation":[{"name":"Center for Gait and Movement Analysis Children\u2019s Hospital Colorado  Aurora CO USA"},{"name":"Department of Physical Medicine &amp; Rehabilitation University of Colorado Anschutz Medical Campus  Aurora CO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Tagawa","sequence":"additional","affiliation":[{"name":"Center for Gait and Movement Analysis Children\u2019s Hospital Colorado  Aurora CO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Carollo","sequence":"additional","affiliation":[{"name":"Center for Gait and Movement Analysis Children\u2019s Hospital Colorado  Aurora CO USA"},{"name":"Department of Physical Medicine &amp; Rehabilitation University of Colorado Anschutz Medical Campus  Aurora CO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,4,2]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2006.03.011"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ocl.2010.06.004"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2009.03.009"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1891\/9781617052255.0014"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ocl.2010.06.007"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.3233\/PRM-180585"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2007.00647.x"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2008.03196.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1891\/9781617052255.0005"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/17453670610013448"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.bpo.0000229970.55694.5c"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/01241398-199414060-00001"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2008.03250.x"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2008.03115.x"},{"key":"e_1_2_8_16_1","volume-title":"International Classification of Functioning","author":"World Health Organization","year":"2001"},{"key":"e_1_2_8_17_1","first-page":"1015","article-title":"Advances in patient reported outcomes: the NIH PROMIS measures","volume":"1","author":"Broderick JE","year":"2013","journal-title":"EGEMS (Wash DC)"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-011-9990-8"},{"key":"e_1_2_8_19_1","first-page":"S53","article-title":"The promise of PROMIS: using item response theory to improve assessment of patient\u2010reported outcomes","volume":"23","author":"Fries JF","year":"2005","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.13138"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.14368"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1302\/1863-2548.12.170127"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.14148"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2009.04.004"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/0167-9457(91)90046-Z"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2008.05.001"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2017.12.017"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2009.05.020"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2012.11.005"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2015.05.024"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1123\/jpah.5.1.146"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.bpo.0000191553.26574.27"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.3233\/NRE-171465"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40271-013-0028-x"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1123\/japa.2014-0116"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.14871"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4637.2011.01094.x"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1080\/16501970310018305"}],"container-title":["Developmental Medicine &amp; 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