{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T04:52:46Z","timestamp":1793940766246,"version":"4.8.0"},"reference-count":55,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,6,30]],"date-time":"2022-06-30T00:00:00Z","timestamp":1656547200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To examine the prevalence and temporal trends of cerebral palsy (CP) overall and by population characteristics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>\n                      We identified 2\u2009110\u2009177 live births born in the province of Ontario, Canada, between 2002 and 2017 using administrative health data and estimated CP prevalence in children aged 0 to 16\u2009years overall and by specific population characteristics. We also examined temporal trends in CP rates\u00a0\u2013\u00a0overall and by characteristics\u00a0\u2013\u00a0in young children (0\u20134\u2009years) by their year of birth between 2002 and 2013 (\n                      <jats:italic>n<\/jats:italic>\n                      =1\u2009587\u2009087 live births) to allow for an equal follow\u2010up time (4\u2009years and 364\u2009days) for all children.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Overall CP prevalence among children aged 0 to 16\u2009years was 2.52 (95% confidence interval 2.45\u20132.59) per 1000 live births. CP rates in ages 0 to 4\u2009years peaked at 2.86 in 2007 births, but steadily declined afterwards to 1.94 per 1000 live births in 2013. CP rates were higher in children born preterm, small for gestational age, males, multiples, children with congenital malformations, and in children of young (&lt;20\u2009years), old (\u226540\u2009years), primiparous, or grand multiparous (\u22654) mothers; differences by these characteristics decreased over time. We observed socioeconomic disparities in CP rates that persisted over time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interpretation<\/jats:title>\n                    <jats:p>Despite the decreasing trend of CP rates overall, CP rates varied by the child and maternal characteristics over time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>What this paper adds<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>Overall cerebral palsy (CP) prevalence was 2.5 per 1000 live births among children born from 2002 to 2017.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>CP prevalence peaked in children born in 2007 then steadily decreased between 2007 and 2013.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Changes in CP rates varied over time by child and maternal characteristics.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Socioeconomic inequalities in CP persisted and remained stable over the study period.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dmcn.15324","type":"journal-article","created":{"date-parts":[[2022,6,30]],"date-time":"2022-06-30T12:46:09Z","timestamp":1656593169000},"page":"243-253","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Prevalence and temporal trends of cerebral palsy in children born from 2002 to 2017 in Ontario, Canada: Population\u2010based cohort study"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8690-2264","authenticated-orcid":false,"given":"Asma","family":"Ahmed","sequence":"first","affiliation":[{"name":"Department of Epidemiology, Biostatistics and Occupational Health McGill University  Quebec Canada"},{"name":"Child Health Evaluative Sciences The Hospital for Sick Children Research Institute  Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura C.","family":"Rosella","sequence":"additional","affiliation":[{"name":"Dalla Lana School of Public Health, Division of Epidemiology University of Toronto  Toronto Ontario Canada"},{"name":"ICES  Toronto Ontario Canada"},{"name":"Institute for Better Health Trillium Health Partners  Mississauga Ontario Canada"},{"name":"Temerty Faculty of Medicine, Department of Laboratory Medicine and Pathology University of Toronto  Toronto Ontario 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