{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,8]],"date-time":"2026-11-08T00:52:10Z","timestamp":1794099130159,"version":"4.8.0"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,7,28]],"date-time":"2022-07-28T00:00:00Z","timestamp":1658966400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004875","name":"Norrbacka-Eugeniastiftelsen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004875","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006741","name":"Stiftelsen Frimurare Barnhuset i Stockholm","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006741","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003514","name":"Kommunfullm\u00e4ktige, Stockholms Stad","doi-asserted-by":"publisher","award":["1411\u20101372"],"award-info":[{"award-number":["1411\u20101372"]}],"id":[{"id":"10.13039\/501100003514","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003514","name":"Kommunfullm\u00e4ktige, Stockholms Stad","doi-asserted-by":"publisher","award":["20150153"],"award-info":[{"award-number":["20150153"]}],"id":[{"id":"10.13039\/501100003514","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["2016\u201001009"],"award-info":[{"award-number":["2016\u201001009"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["521\u20102013\u20103096"],"award-info":[{"award-number":["521\u20102013\u20103096"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2023,3]]},"abstract":"Abstract<\/jats:title>\n \n Aim<\/jats:title>\n To describe the development of the use of the affected hand in bimanual tasks in children with unilateral cerebral palsy (CP) from 18\u2009months to 18\u2009years. Specifically, whether early development can be confirmed in a larger cohort and how development progresses during adolescence.<\/jats:p>\n <\/jats:sec>\n \n Method<\/jats:title>\n \n In total, 171 participants (95 males, 76 females; mean age 3\u2009years 1\u2009month [SD 3\u2009years 8\u2009months], range 18\u2009months\u201316\u2009years at inclusion) were classified in Manual Ability Classification System (MACS) levels I (\n n<\/jats:italic>\n \u00a0=\u00a041), II (\n n<\/jats:italic>\n \u00a0=\u00a091), and III (\n n<\/jats:italic>\n \u00a0=\u00a039). Children were assessed repeatedly (median 7, range 2\u201316 times) with the Assisting Hand Assessment: in total 1197 assessments. Developmental trajectories were estimated using a nonlinear mixed effects model. To further analyse the adolescent period, a linear mixed model was applied.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The developmental trajectories were different between participants in MACS levels (MACS I\u2013II, II\u2013III) in both rate (0.019, 95% confidence interval [CI] 0.006\u20130.031,\n p<\/jats:italic>\n \u00a0=\u00a00.034; 0.025, 95% CI 0.015\u20130.037,\n p<\/jats:italic>\n \u2009<\u20090.001) and limit (19.9, 95% CI 16.6\u201323.3,\n p<\/jats:italic>\n \u00a0=\u00a00.001; 7.2, 95% CI 3.3\u201311.2,\n p<\/jats:italic>\n \u2009<\u20090.003). The individual variations were large within each level. The developmental trajectories were stable over time for all MACS levels between 7 and 18\u2009years (\n p<\/jats:italic>\n \u2009>\u20090.05).\n <\/jats:p>\n <\/jats:sec>\n \n Interpretation<\/jats:title>\n Children and adolescents with unilateral CP have considerable development at an early age and a stable ability to use their affected hand in bimanual activities from 7 to 18\u2009years in all MACS levels.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/dmcn.15370","type":"journal-article","created":{"date-parts":[[2022,7,28]],"date-time":"2022-07-28T07:38:23Z","timestamp":1658993903000},"page":"376-384","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Longitudinal development of hand use in children with unilateral spastic cerebral palsy from 18\u2009months to 18\u2009years"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7527-3810","authenticated-orcid":false,"given":"Ann\u2010Christin","family":"Eliasson","sequence":"first","affiliation":[{"name":"Department of Women's and Children's Health, Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Nordstrand","sequence":"additional","affiliation":[{"name":"Department of Neurobiology, Care Sciences and Society, Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnus","family":"Backheden","sequence":"additional","affiliation":[{"name":"Department of Leaning, Informatics, Management and Ethics, Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5418-3154","authenticated-orcid":false,"given":"Marie","family":"Holmefur","sequence":"additional","affiliation":[{"name":"School of Health Sciences \u00d6rebro University \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,7,28]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"crossref","unstructured":"HimmelmannK UvebrantP.The panorama of cerebral palsy in Sweden part XII shows that patterns changed in the birth years 2007\u20132010. 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