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SWA was lower in patients compared to controls in the first hour of non\u2010rapid eye movement sleep (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.021), although not in those who remained seizure\u2010free (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.26). Full\u2010scale IQ did not correlate with measures of SWA in patients or controls. There was no significant difference in SWA measures between focal and non\u2010focal electrodes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interpretation<\/jats:title>\n                    <jats:p>Overnight SWA decline is conserved in children with focal epilepsy and may underpin the preservation of sleep\u2010related memory consolidation in this patient group. Reduced early\u2010night SWA may reflect impaired or immature sleep homeostasis in those with a higher seizure burden.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>What this paper adds<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>The decline in slow\u2010wave activity (SWA) across the night, reflecting global synaptic downscaling, was preserved in children with focal lesional epilepsies.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Sleep benefited memory consolidation in this group of patients, as in typically developing children.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Reduced early\u2010night SWA was associated with increased likelihood of a subsequent seizure.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dmcn.15403","type":"journal-article","created":{"date-parts":[[2022,9,7]],"date-time":"2022-09-07T03:43:55Z","timestamp":1662522235000},"page":"701-711","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Sleep homeostasis, seizures, and cognition in children with focal\u00a0epilepsy"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6869-5804","authenticated-orcid":false,"given":"Maria H.","family":"Eriksson","sequence":"first","affiliation":[{"name":"Developmental Neurosciences Research &amp; Teaching Department UCL Great Ormond Street Institute of Child Health  London UK"},{"name":"Neuropsychology, Great Ormond Street Hospital NHS Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torsten","family":"Baldeweg","sequence":"additional","affiliation":[{"name":"Developmental Neurosciences Research &amp; Teaching Department UCL Great Ormond Street Institute of Child Health  London UK"},{"name":"Neuropsychology, Great Ormond Street Hospital NHS Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronit","family":"Pressler","sequence":"additional","affiliation":[{"name":"Neurophysiology, Great Ormond Street Hospital NHS Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stewart G.","family":"Boyd","sequence":"additional","affiliation":[{"name":"Neurophysiology, Great Ormond Street Hospital NHS Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reto","family":"Huber","sequence":"additional","affiliation":[{"name":"Children's Research Center University Children's Hospital Zurich  Zurich Switzerland"},{"name":"Child Development Center University Children's Hospital Zurich  Zurich Switzerland"},{"name":"Department of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric Hospital University of Zurich  Zurich Switzerland"},{"name":"Pediatric Sleep Disorders Center University Children's Hospital Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Helen","family":"Cross","sequence":"additional","affiliation":[{"name":"Developmental Neurosciences Research &amp; Teaching Department UCL Great Ormond Street Institute of Child Health  London UK"},{"name":"Neurology, Great Ormond Street Hospital NHS Trust  London UK"},{"name":"Young Epilepsy, Lingfield  UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bigna K.","family":"B\u00f6lsterli","sequence":"additional","affiliation":[{"name":"Children's Research Center University Children's Hospital Zurich  Zurich Switzerland"},{"name":"Department of Pediatric Neurology University Children's Hospital Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0488-1207","authenticated-orcid":false,"given":"Samantha Y. 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