{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T09:37:09Z","timestamp":1768556229312,"version":"3.49.0"},"reference-count":30,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,2,12]],"date-time":"2023-02-12T00:00:00Z","timestamp":1676160000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To determine indications and prescribing patterns for antiseizure medications (ASMs) in children by age, sex, and socioeconomic status.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This retrospective study searched the New Zealand database of ASM prescriptions dispensed to individuals aged 18\u2009years or under during 2015 in three regions of New Zealand (48% paediatric population). Medical records were reviewed by a paediatric neurologist for indication. ASMs were grouped into old or new (1993 onwards).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 2594 children (0 to 18\u2009years, mean age 11\u2009years 2\u2009months, median 12\u2009years; 51% male) were dispensed 3557 ASMs for seizures (76%), pain (6%), headache (5%), mental health (3%), and movement disorders (2%). After 10\u2009years of age, lamotrigine was more likely and valproate less likely to be prescribed in females than males. No sex difference was observed for valproate prescriptions for non\u2010seizure indications. Topiramate prescriptions increased in adolescent females. Prescriptions for non\u2010seizure indications increased from 7% in children aged 6\u2009years or under to 31% in 16\u2010 to 18\u2010year\u2010olds. The proportion of children receiving a new ASM compared to an old ASM was greater in children from higher than lower socioeconomic areas.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interpretation<\/jats:title><jats:p>Our results highlight a need for focused ASM teratogenicity messaging to clinicians prescribing ASMs for non\u2010seizure indications. In addition, to improve equity of epilepsy care, it is critical for health policies to consider socioeconomic factors that impact on ASM prescribing.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dmcn.15546","type":"journal-article","created":{"date-parts":[[2023,2,13]],"date-time":"2023-02-13T04:09:30Z","timestamp":1676261370000},"page":"1247-1255","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Indications and prescribing patterns of antiseizure medications in children in New Zealand"],"prefix":"10.1111","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9177-4938","authenticated-orcid":false,"given":"Shayma","family":"Ali","sequence":"first","affiliation":[{"name":"Department of Paediatrics and Child Health University of Otago  Wellington New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Stanley","sequence":"additional","affiliation":[{"name":"Department of Public Health University of Otago  Wellington New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne","family":"Davis","sequence":"additional","affiliation":[{"name":"Department of Neurology Auckland City Hospital  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ngaire","family":"Keenan","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Child Health University of Otago  Wellington New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2311-2174","authenticated-orcid":false,"given":"Ingrid E.","family":"Scheffer","sequence":"additional","affiliation":[{"name":"Departments of Medicine and Paediatrics University of Melbourne, Austin Health and Royal Children's Hospital, Florey and Murdoch Children's Research Institutes  Melbourne 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