{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T10:53:09Z","timestamp":1788691989970,"version":"build-2803163510"},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,7,21]],"date-time":"2023-07-21T00:00:00Z","timestamp":1689897600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2024,2]]},"abstract":"Abstract<\/jats:title>Aim<\/jats:title>We investigated survival rates after scoliosis correction in individuals with Duchenne muscular dystrophy (DMD) and evaluated factors that can affect them.<\/jats:p><\/jats:sec>Method<\/jats:title>This was a retrospective cohort study from 2000 to 2022 with a minimum 2\u2010year postoperative follow\u2010up. We reviewed the hospital records\/spinal radiographs and analysed data with XLSTAT. Kaplan\u2013Meier and multivariate Cox regression survival analysis was performed.<\/jats:p><\/jats:sec>Results<\/jats:title>Forty\u2010three patients had a mean age at surgery of 14\u2009years 5\u2009months. Mean postoperative follow\u2010up was 10\u2009years 10\u2009months. There was no operative or 30\u2010day postoperative mortality in this group. Twenty\u2010four patients died because of cardiorespiratory failure. Median survivorship was 14\u2009years 2\u2009months, with the longest observed survival being 22\u2009years 6\u2009months given the limitation of the length of postoperative follow\u2010up. The degree of preoperative coronal imbalance and pelvic obliquity, as well as intraoperative blood loss, were factors that significantly affected survival. The impact of preoperative sagittal imbalance and extension of the fusion to the sacrum\/pelvis trended towards significance. In contrast, age at surgery, preoperative\/postoperative scoliosis, thoracic kyphosis, lumbar lordosis, scoliosis and pelvic obliquity flexibility or correction indices, postoperative coronal\/sagittal balance, need of preoperative non\u2010invasive ventilation, preoperative feeding disorders, development of surgical complications, and length of hospital and intensive care unit stay were exposure variables that did not affect postsurgical survival in patients with DMD.<\/jats:p><\/jats:sec>Interpretation<\/jats:title>Survival of up to two decades or more was possible among young patients with DMD after scoliosis correction. This was affected by factors that related to disease and deformity severity, as well as surgical morbidity.<\/jats:p><\/jats:sec>What this paper adds<\/jats:title>\n\nThere was no operative or 30\u2010day postoperative mortality in this group of patients with Duchenne muscular dystrophy (DMD) undergoing scoliosis correction.<\/jats:p><\/jats:list-item>\nSurvival probabilities at 5\u2010year, 10\u2010year, 15\u2010year, and 20\u2010year intervals post\u2010surgery were 92%, 80%, 33%, and 12% respectively.<\/jats:p><\/jats:list-item>\nScoliosis surgery achieved good deformity correction and a balanced spine that was maintained at follow\u2010up.<\/jats:p><\/jats:list-item>\nRespiratory failure, severe pneumonia, and left ventricular failure were the leading causes of death in the study participants.<\/jats:p><\/jats:list-item>\nPreoperative global coronal imbalance, pelvic obliquity, and intraoperative blood loss significantly predicted survival.<\/jats:p><\/jats:list-item>\nFactors that affected survival after scoliosis surgery were associated with perioperative morbidity and disease or deformity severity in the DMD group.<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p><\/jats:sec>","DOI":"10.1111\/dmcn.15711","type":"journal-article","created":{"date-parts":[[2023,7,22]],"date-time":"2023-07-22T06:08:10Z","timestamp":1690006090000},"page":"187-194","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Survival of patients with Duchenne muscular dystrophy who underwent spinal deformity correction"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9562-2675","authenticated-orcid":false,"given":"Ayesha","family":"Arshad","sequence":"first","affiliation":[{"name":"Scottish National Spine Deformity Centre Royal Hospital for Children and Young People Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2339-5327","authenticated-orcid":false,"given":"Athanasios I.","family":"Tsirikos","sequence":"additional","affiliation":[{"name":"Scottish National Spine Deformity Centre Royal Hospital for Children and Young People Edinburgh 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Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dmcn.15711","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T19:17:29Z","timestamp":1734463049000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/dmcn.15711"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,21]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["10.1111\/dmcn.15711"],"URL":"https:\/\/doi.org\/10.1111\/dmcn.15711","archive":["Portico"],"relation":{},"ISSN":["0012-1622","1469-8749"],"issn-type":[{"value":"0012-1622","type":"print"},{"value":"1469-8749","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,21]]},"assertion":[{"value":"2022-10-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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