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Barriers and facilitators to participation were categorized into four factors: personal, social, environmental, and policy and programme. Findings were analysed and validated by a young adult with Down syndrome and a family member, using the public and patient involvement strategy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fourteen studies were included: eight with children and adolescents and six with adults. Of the 14 studies, 10 were qualitative and four quantitative. Most studies (<jats:italic>n<\/jats:italic>\u2009=\u20099) investigated participation in physical activities, while only a few examined participation in community\/social activities (<jats:italic>n<\/jats:italic>\u2009=\u20093), daily activities (<jats:italic>n<\/jats:italic>\u2009=\u20092), and leisure activities (<jats:italic>n<\/jats:italic>\u2009=\u20091). The most commonly cited barriers and facilitators were the availability of programmes and specialized professionals, transportation, as well as attitudes and behaviours. Physical and psychological characteristics of people with Down syndrome and facilities were also frequently mentioned as barriers. On the other hand, the desire to stay active and personal interest in the activity were among the most frequently reported facilitators.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interpretation<\/jats:title><jats:p>The participation of people with Down syndrome is mainly influenced by physical or psychological factors, the support and attitudes of parents\/caregivers, and the availability of specialized programmes. Given the scarcity of research investigating the participation of people with Down syndrome in community activities, daily activities, and leisure, especially in adults, more studies are still needed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dmcn.15857","type":"journal-article","created":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T07:34:41Z","timestamp":1707291281000},"page":"1013-1030","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["What are the barriers and facilitators to participation of people with Down syndrome? A scoping review"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8730-643X","authenticated-orcid":false,"given":"Deisiane Oliveira","family":"Souto","sequence":"first","affiliation":[{"name":"Graduate Programme in Rehabilitation Sciences, Physical Therapy Department, School of Physical Education, Physical Therapy and Occupational Therapy Universidade Federal de Minas Gerais  Belo Horizonte Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina Oliveira","family":"de Sousa","sequence":"additional","affiliation":[{"name":"Graduate Programme in Rehabilitation Sciences, Physical Therapy Department, School of Physical Education, Physical Therapy and Occupational Therapy Universidade Federal de Minas Gerais  Belo Horizonte Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafaela Guimar\u00e3es","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Graduate Programme in Rehabilitation Sciences, 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