{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:20:23Z","timestamp":1791930023009,"version":"4.3.4"},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,10,16]],"date-time":"2024-10-16T00:00:00Z","timestamp":1729036800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To describe the impact of paediatric myelin oligodendrocyte glycoprotein antibody\u2010associated disease (MOGAD) on academic and cognitive outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This was an observational, retrospective, and descriptive single\u2010centre study, carried out on a paediatric case series of children with MOGAD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 51 patients were included (22 females); their median age was 8\u2009years and the median follow\u2010up duration was 31.1\u2009months (interquartile range 23.5). The most frequent clinical presentation was acute disseminated encephalomyelitis (54.9%), followed by optic neuritis (35.5%). At the last follow\u2010up, regardless of the clinical phenotype at disease onset, 39.5% of patients with MOGAD received academic and educational interventions (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05 compared to before disease onset), including academic accommodations (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05) or the need for a learning support assistant (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). Ten patients were evaluated with the Wechsler Intelligence Scale for Children, Fifth Edition (WISC\u2010V). The overall IQ was calculated for six patients (mean\u2009=\u200992); two of these patients had an IQ\u2009lower than\u200985. No difference was found regarding prenatal and neonatal neurodevelopmental characteristics between this cohort and the general population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interpretation<\/jats:title><jats:p>MOGAD was associated with a need for academic support; lower scores were found on the WISC\u2010V. Patients with MOGAD should receive cognitive and academic assessments to inform educational planning and support academic success.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dmcn.16093","type":"journal-article","created":{"date-parts":[[2024,10,16]],"date-time":"2024-10-16T10:45:41Z","timestamp":1729075541000},"page":"529-536","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Cognitive and academic outcomes in children\u2009with myelin oligodendrocyte glycoprotein antibody\u2010associated disease"],"prefix":"10.1111","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-6273-3054","authenticated-orcid":false,"given":"Audrey","family":"Mittelman","sequence":"first","affiliation":[{"name":"Centre de R\u00e9f\u00e9rence des Maladies Inflammatoires Rares du Cerveau et de la Moelle (MIRCEM)  Lyon France"},{"name":"Service de Neurop\u00e9diatrie H\u00f4pital Femme M\u00e8re Enfant  Lyon 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