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The snapshot of the disease progression at a particular time point, lack of cooperation by the children during assessments, and susceptibility to bias limit the utility of these measures. Wearable sensors, which capture data continuously in natural settings, offer a non\u2010invasive and objective alternative to traditional methods. This review examines the role of wearable sensors in various paediatric neurological conditions, including cerebral palsy, epilepsy, autism spectrum disorder, attention\u2010deficit\/hyperactivity disorder, as well as Rett syndrome, Down syndrome, Angelman syndrome, Prader\u2013Willi syndrome, neuromuscular disorders such as Duchenne muscular dystrophy and spinal muscular atrophy, ataxia, Gaucher disease, headaches, and sleep disorders. The review highlights their application in tracking motor function, seizure activity, and daily movement patterns to gain insights into disease progression and therapeutic response. Although challenges related to population size, compliance, ethics, and regulatory approval remain, wearable technology promises to improve clinical trials and outcomes for patients in paediatric neurology.<\/jats:p>","DOI":"10.1111\/dmcn.16239","type":"journal-article","created":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T13:13:51Z","timestamp":1738329231000},"page":"834-853","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Wearable sensors in paediatric neurology"],"prefix":"10.1111","volume":"67","author":[{"given":"Camila","family":"Gonz\u00e1lez Barral","sequence":"first","affiliation":[{"name":"Sysnav  Vernon France"},{"name":"Neuromuscular Reference Center, Department of Pediatrics University Hospital Li\u00e8ge  Belgium"},{"name":"Faculty of Medicine, Department of clinical sciences University of Li\u00e8ge  Li\u00e8ge Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9270-4061","authenticated-orcid":false,"given":"Laurent","family":"Servais","sequence":"additional","affiliation":[{"name":"Neuromuscular Reference Center, Department of Pediatrics University Hospital Li\u00e8ge  Belgium"},{"name":"Faculty of Medicine, Department of clinical sciences University of Li\u00e8ge  Li\u00e8ge Belgium"},{"name":"MDUK Oxford Neuromuscular Centre University of Oxford  Oxford UK"},{"name":"NIHR Oxford Biomedical Research Centre University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,31]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(24)00038-3"},{"key":"e_1_2_10_3_1","first-page":"1","article-title":"Lessons from a negative gene therapy trial for Duchenne muscular dystrophy","volume":"9","author":"Spuler S","year":"2024","journal-title":"Nat Med."},{"key":"e_1_2_10_4_1","unstructured":"WuM PhD Luo J Contributors POJ of NI. 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