{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:08:07Z","timestamp":1790744887790,"version":"4.1.0"},"reference-count":29,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T00:00:00Z","timestamp":1746662400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012256","name":"Cerebral Palsy Alliance Research Foundation","doi-asserted-by":"publisher","award":["PRG00123"],"award-info":[{"award-number":["PRG00123"]}],"id":[{"id":"10.13039\/100012256","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["GNT1149332"],"award-info":[{"award-number":["GNT1149332"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To explore factors contributing to the burden of respiratory admissions in children with severe cerebral palsy (CP) by comparing admissions to a single tertiary paediatric hospital before, during, and after the period of social restrictions implemented to reduce transmission of COVID\u201019 (lockdown period).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>For this observational study, three severe CP cohorts (pre\u2010lockdown, lockdown, post\u2010lockdown) were identified from a state\u2010wide cerebral palsy register and linked to patient\u2010level clinical and demographic data. Medical records were manually searched to identify respiratory hospitalizations. Frequency and details of admissions were compared across the three 2\u2010year periods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      During the lockdown period, there were 24 hospitalizations for respiratory illness per 100 children compared to 37 and 47 in the pre\u2010lockdown and post\u2010lockdown periods (\n                      <jats:italic>p<\/jats:italic>\n                      &lt;\u20090.001). Respiratory viruses (excluding picornaviruses) were detected in only 7% of lockdown admissions compared to 24% pre\u2010lockdown and 30% post\u2010lockdown. Sputum sampling was performed in 34% of admissions with gram\u2010positive bacteria cultured in 6% admissions and gram\u2010negative bacteria only in 18%.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interpretation<\/jats:title>\n                    <jats:p>The study findings highlight an important dynamic contribution of viral infections to respiratory illnesses in children with severe CP and the potential to improve outcomes with personalized approaches based on defining individual factors predisposing to recurrent respiratory admissions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dmcn.16346","type":"journal-article","created":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T02:41:04Z","timestamp":1746758464000},"page":"1582-1589","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Respiratory admissions and impact of\n                    <scp>COVID<\/scp>\n                    \u201019 lockdowns for children with severe cerebral palsy"],"prefix":"10.1111","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9415-5246","authenticated-orcid":false,"given":"Susan M.","family":"Reid","sequence":"first","affiliation":[{"name":"Neurodisability and Rehabilitation Murdoch Children's Research Institute  Parkville Victoria Australia"},{"name":"Department of Paediatrics University of Melbourne  Parkville Victoria Australia"},{"name":"Department of Neurodevelopment and Disability The Royal Children's Hospital  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moya","family":"Vendeleur","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Sleep Medicine The Royal Children's Hospital  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Wurzel","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Sleep Medicine The Royal Children's Hospital  Parkville Victoria Australia"},{"name":"Respiratory Diseases Group Murdoch Children's Research Institute  Parkville Victoria Australia"},{"name":"Allergy and Lung Health Unit, School of Population and Global Health University of Melbourne  Parkville Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Frayman","sequence":"additional","affiliation":[{"name":"Department of Paediatrics University of Melbourne  Parkville Victoria Australia"},{"name":"Department of Respiratory and Sleep Medicine The Royal Children's Hospital  Parkville Victoria Australia"},{"name":"Respiratory Diseases Group Murdoch Children's Research Institute  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Osowicki","sequence":"additional","affiliation":[{"name":"Department of Paediatrics University of Melbourne  Parkville Victoria Australia"},{"name":"Tropical Diseases Research Group Murdoch Children's Research Institute  Parkville Victoria Australia"},{"name":"Department of Infectious Diseases The Royal Children's Hospital  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kylie","family":"Crompton","sequence":"additional","affiliation":[{"name":"Neurodisability and Rehabilitation Murdoch Children's Research Institute  Parkville Victoria Australia"},{"name":"Department of Paediatrics University of Melbourne  Parkville Victoria Australia"},{"name":"Department of Neurodevelopment and Disability The Royal Children's Hospital  Parkville Victoria 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