{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T15:08:44Z","timestamp":1780585724013,"version":"3.54.1"},"reference-count":30,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T00:00:00Z","timestamp":1763337600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T00:00:00Z","timestamp":1763337600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>\n                      This is a case series of neonates born near term presenting with periventricular haemorrhagic infarction (PVHI), determining possible risk factors, clinical presentation, magnetic resonance imaging (MRI), and amplitude\u2010integrated electroencephalography (aEEG) characteristics, and neurodevelopmental outcomes. Twenty term\u2010born neonates, diagnosed with PVHI less than 4\u2009weeks after birth were included. Clinical characteristics and presenting symptoms were gathered from electronic patient records. PVHI anatomical venous subtype involvement was classified on MRI. aEEG recordings were scored on background activity, sleep\u2013wake cycling, and seizures. Neurodevelopmental outcome was assessed at median age of 5\u2009years 10\u2009months. The majority of neonates (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u200919) presented with seizures around the second day after birth. Methylenetetrahydrofolate reductase mutations were present in 10 out of 11. The caudate vein territory was most commonly involved (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u200911). aEEG patterns in the first 24\u2009hours after symptoms showed more discontinuous background and less sleep\u2013wake cycling in the ipsilesional hemispheres. PVHI in term\u2010born neonates most often presents with seizures. Neonatal complications during pregnancy and delivery and prothrombotic genetic mutations were slightly more common in this group.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dmcn.70055","type":"journal-article","created":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T07:50:00Z","timestamp":1763452200000},"page":"1005-1012","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Neonates born at term with periventricular haemorrhagic infarction: Risk factors and clinical presentation"],"prefix":"10.1111","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-5503-7839","authenticated-orcid":false,"given":"Aleksandra","family":"Zaykova","sequence":"first","affiliation":[{"name":"Department of Neonatology Wilhelmina Children's Hospital, University Medical Centre Utrecht  Utrecht 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