{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T04:02:40Z","timestamp":1789358560557,"version":"build-2803163510"},"reference-count":34,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T00:00:00Z","timestamp":1768694400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T00:00:00Z","timestamp":1768694400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100007382","name":"Fondation Motrice","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007382","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To assess the effect of the augmented reality application called Minidocs on pain reduction during botulinum neurotoxin A (BoNT\u2010A) injections in children with cerebral palsy (CP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>\n                      Children with CP aged 3 to 8\u2009years undergoing BoNT\u2010A injection were randomized to usual pain management alone (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u200941) or combined with Minidocs (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u200939). Minidocs is an augmented reality application on a digital device offering several games including active distraction, hypnotic suggestion, and counter\u2010aggression features. The primary outcome was the child's pain during BoNT\u2010A injection, combining patient\u2010reported (Faces Pain Scale [FPS]) and observer\u2010reported (Face, Legs, Activity, Cry, Consolability scale [FLACC]) outcomes. Secondary outcomes included anxiety of children (Modified Yale Preoperative Anxiety Scale) and parents (State\u2013Trait Anxiety Inventory Form Y\u20101), and satisfaction with Minidocs.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In total, 14 out of 41 (34.1%) children in the control group and 7 out of 39 (17.9%) children in the experimental group experienced pain (i.e. FPS or FLACC scores \u22654). The difference between groups was not statistically significant (odds ratio 0.36; 95% confidence interval 0.11\u20131.16;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u20090.087). Changes in anxiety scores from before to after injection did not differ between groups. Satisfaction with the use of Minidocs was high.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interpretation<\/jats:title>\n                    <jats:p>This study did not demonstrate the benefit of augmented reality on pain reduction. The counter\u2010aggression feature is an innovation of Minidocs worth exploring. Further studies are needed to identify profiles of children who respond to non\u2010drug therapies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dmcn.70143","type":"journal-article","created":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T04:20:49Z","timestamp":1768796449000},"page":"1152-1160","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Augmented reality and pain during botulinum neurotoxin A injections in children with cerebral palsy: A randomized controlled trial"],"prefix":"10.1111","volume":"68","author":[{"given":"Emmanuelle","family":"Chal\u00e9at\u2010Valayer","sequence":"first","affiliation":[{"name":"Massues Rehabilitation Center \u2013 French Red Cross  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aur\u00e9lie","family":"Lucet","sequence":"additional","affiliation":[{"name":"Bois Larris Rehabilitation Center for Children \u2013 French Red Cross  Lamorlaye France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ang\u00e9lique","family":"Denis","sequence":"additional","affiliation":[{"name":"Hospices Civils de Lyon, Public Health Department Biostatistics and Bioinformatics Unit  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandrine","family":"Touzet","sequence":"additional","affiliation":[{"name":"Hospices Civils de Lyon, Public Health Department Clinical Research and Epidemiology Unit  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Rouch","sequence":"additional","affiliation":[{"name":"CHU de Saint\u2010Etienne Neurology Unit  Saint\u2010Etienne France"},{"name":"INSERM U 1219, ACTIVE Team, Bordeaux Population Health Bordeaux University  Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4386-0946","authenticated-orcid":false,"given":"Rachel","family":"Bard\u2010Pondarr\u00e9","sequence":"additional","affiliation":[{"name":"Massues Rehabilitation Center \u2013 French Red Cross  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Am\u00e9lie","family":"Zelmar","sequence":"additional","affiliation":[{"name":"Hospices Civils de Lyon, Public Health Department Clinical Research and Epidemiology Unit  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4888-0815","authenticated-orcid":false,"given":"Olivia","family":"Febvey\u2010Combes","sequence":"additional","affiliation":[{"name":"Hospices Civils de Lyon, Public Health Department Clinical Research and Epidemiology Unit  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,18]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.16274"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61013-7"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61229-0"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rehab.2009.09.001"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpn.2010.04.006"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcped.2017.11.012"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2008.03069.x"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annrmp.2007.02.003"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1207\/s15324796abm3003_11"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0b013e3181aaa909"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/pan.14546"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2019.02.034"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.2196\/25499"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10877-021-00705-0"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2007.10.010"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/pan.13395"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1213\/XAA.0000000000001219"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(01)00314-1"},{"key":"e_1_2_9_20_1","first-page":"140","article-title":"Clinical validation of FLACC: preverbal patient pain scale","volume":"29","author":"Manworren RC","year":"2003","journal-title":"Pediatr Nurs"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9592.2008.02655.x"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2018.02.013"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-199710000-00012"},{"key":"e_1_2_9_24_1","volume-title":"State\u2010Trait Anxiety Inventory: Bibliography","author":"Spielberger CD","year":"1989"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(00)00269-4"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2011.01.050"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.14204"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rehab.2018.12.004"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sjpain.2017.07.014"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2020.00723"},{"key":"e_1_2_9_31_1","first-page":"277","article-title":"The power of swearing: What we know and what we don't","author":"Stapleton K","year":"2022","journal-title":"Lingua"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4637.2006.00086.x"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.2147\/JPR.S267839"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.3928\/19382359-20170921-03"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rehab.2014.09.010"}],"container-title":["Developmental Medicine &amp; Child Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dmcn.70143","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/dmcn.70143","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dmcn.70143","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T03:15:46Z","timestamp":1789355746000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/dmcn.70143"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,18]]},"references-count":34,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1111\/dmcn.70143"],"URL":"https:\/\/doi.org\/10.1111\/dmcn.70143","archive":["Portico"],"relation":{},"ISSN":["0012-1622","1469-8749"],"issn-type":[{"value":"0012-1622","type":"print"},{"value":"1469-8749","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,18]]},"assertion":[{"value":"2024-09-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}