{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T04:02:38Z","timestamp":1789358558834,"version":"build-2803163510"},"reference-count":33,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T00:00:00Z","timestamp":1768348800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T00:00:00Z","timestamp":1768348800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100005693","name":"Parent Project Muscular Dystrophy","doi-asserted-by":"publisher","award":["24MG\u2010PG12"],"award-info":[{"award-number":["24MG\u2010PG12"]}],"id":[{"id":"10.13039\/100005693","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007423","name":"Duchenne Parent Project","doi-asserted-by":"publisher","award":["24.003"],"award-info":[{"award-number":["24.003"]}],"id":[{"id":"10.13039\/501100007423","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007423","name":"Duchenne Parent Project","doi-asserted-by":"publisher","award":["DUK\u20102024\u201006"],"award-info":[{"award-number":["DUK\u20102024\u201006"]}],"id":[{"id":"10.13039\/501100007423","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","award":["847826"],"award-info":[{"award-number":["847826"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To develop a brief, reliable, and valid screening tool and to provide normative data for the identification of individuals with Duchenne muscular dystrophy (DMD) at risk of brain\u2010related comorbidities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>An 18\u2010item proxy\/self\u2010report screening tool covering nine comorbidity areas was developed on the basis of existing literature and expert consensus, and translated into 11 languages. In this cross\u2010sectional observational study, data from 835 individuals with DMD (aged 5\u201342\u2009years) were used to assess reliability, construct validity, and diagnostic accuracy. A subsample of 90 participants completed cognitive and behavioural assessments for concurrent validity analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The Brain Involvement iN Dystrophinopathies (BIND) screener showed excellent internal consistency (\n                      <jats:italic>\u03b1<\/jats:italic>\n                      \u00a0=\u00a00.89) and a factor structure aligned with theoretical domains. Age\u2010related patterns were observed across domains. The total score (Duchenne Brain Comorbidity Score) correlated with clinical and cognitive markers in the validation subsample. Receiver operating characteristic analysis in the full sample yielded an area under the curve of 0.78, with a cut\u2010off score of 20\/72 providing optimal sensitivity (71.6%) and specificity (72.5%) for identifying parent\u2010 or self\u2010reported neurodevelopmental conditions previously diagnosed by professionals.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interpretation<\/jats:title>\n                    <jats:p>The BIND screener is a brief, psychometrically robust tool that facilitates early identification of brain\u2010related comorbidities in DMD and may be applied in both clinical practice and research.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dmcn.70145","type":"journal-article","created":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T08:01:34Z","timestamp":1768377694000},"page":"1080-1096","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Screening for brain\u2010related comorbidities in Duchenne muscular dystrophy: Construction, reliability, and validity of the\n                    <scp>BIND<\/scp>\n                    screener"],"prefix":"10.1111","volume":"68","author":[{"given":"Ruben","family":"Miranda","sequence":"first","affiliation":[{"name":"Department of Psychobiology and Methodology in Behavioral Sciences Universidad Complutense de Madrid  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pien M. M.","family":"Weerkamp","sequence":"additional","affiliation":[{"name":"Kempenhaeghe Centre for Neurological Learning Disabilities  Heeze Netherlands"},{"name":"Maastricht University, School for Mental Health and Neuroscience  Maastricht Netherlands"},{"name":"Leiden University Medical Center, Department of Neurology  Leiden Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Kolesnik","sequence":"additional","affiliation":[{"name":"Dubowitz Neuromuscular Centre, Great Ormond Street Institute of Child Health UCL and NIHR Biomedical Research Centre  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chloe","family":"Geagan","sequence":"additional","affiliation":[{"name":"John Walton Muscular Dystrophy Research Centre, NIHR Newcastle Biomedical Research Centre Newcastle University and Newcastle Hospitals NHS Foundation Trust  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Chieffo","sequence":"additional","affiliation":[{"name":"Department of Paediatric Neurology Catholic University  Rome Italy"},{"name":"Centro Clinico Nemo Fondazione Policlinico Gemelli IRCCS  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana","family":"Su\u00e1rez\u2010Bagnasco","sequence":"additional","affiliation":[{"name":"Department of Psychobiology and Methodology in Behavioral Sciences Universidad Complutense de Madrid  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Skuse","sequence":"additional","affiliation":[{"name":"Dubowitz Neuromuscular Centre, Great Ormond Street Institute of Child Health UCL and NIHR Biomedical Research Centre  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Vroom","sequence":"additional","affiliation":[{"name":"World Duchenne Organization  Veenendaal Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik H.","family":"Niks","sequence":"additional","affiliation":[{"name":"Leiden University Medical Center, Department of Neurology  Leiden Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Vissing","sequence":"additional","affiliation":[{"name":"Copenhagen Neuromuscular Center, Department of Neurology, Rigshospitalet University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Desguerre","sequence":"additional","affiliation":[{"name":"Imagine Institute of Genetic Diseases Necker\u2013Enfants Malades Hospital  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volker","family":"Straub","sequence":"additional","affiliation":[{"name":"John Walton Muscular Dystrophy Research Centre, NIHR Newcastle Biomedical Research Centre Newcastle University and Newcastle Hospitals NHS Foundation Trust  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Muntoni","sequence":"additional","affiliation":[{"name":"Dubowitz Neuromuscular Centre, Great Ormond Street Institute of Child Health UCL and NIHR Biomedical Research Centre  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugenio","family":"Mercuri","sequence":"additional","affiliation":[{"name":"Department of Paediatric Neurology Catholic University  Rome Italy"},{"name":"Centro Clinico Nemo Fondazione Policlinico Gemelli IRCCS  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos G. 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