{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T05:17:43Z","timestamp":1788585463867,"version":"build-2803163510"},"reference-count":42,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T00:00:00Z","timestamp":1771632000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T00:00:00Z","timestamp":1771632000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To describe parental perspectives on how heatwaves and high ambient temperatures influence seizure activity in children and adolescents with Dravet syndrome and to examine coping strategies families employ.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>A descriptive qualitative study was conducted using purposeful, non\u2010probabilistic sampling. Nineteen parents of children and adolescents with Dravet syndrome were interviewed in\u2010depth. Inductive thematic analysis was performed using MAXQDA software.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Three themes emerged: (1) seizure worsening with high ambient temperatures; (2) additional temperature\u2010related triggers; and (3) parental coping strategies. Parents reported that heatwaves and high temperatures increased seizure frequency, intensity, and duration. Abrupt temperature shifts and water exposure (e.g. swimming) were cited as additional triggers. Parents used thermoregulatory measures\u2014light clothing, cool indoor environments, restricted outdoor activity\u2014and empirical antipyretic use to mitigate seizure risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interpretation<\/jats:title>\n                    <jats:p>This research highlights the aggravating role of heatwaves and how parents implement thermoregulation strategies. These findings inform clinical guidance for managing Dravet syndrome during extreme heat, and emphasize the need for further research into the prevention of heat\u2010related seizures.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dmcn.70162","type":"journal-article","created":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T18:30:48Z","timestamp":1771698648000},"page":"1450-1459","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Seizures in children with Dravet syndrome in extreme heat: A\u00a0qualitative study of parental perspectives"],"prefix":"10.1111","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4889-3365","authenticated-orcid":false,"given":"Angel","family":"Aledo\u2010Serrano","sequence":"first","affiliation":[{"name":"Epilepsy Unit, Neurology Department Blua Sanitas Valdebebas Hospital  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7779-7626","authenticated-orcid":false,"given":"Jos\u00e9 \u00c1ngel","family":"Aibar","sequence":"additional","affiliation":[{"name":"Dravet Syndrome Foundation Spain  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0669-6339","authenticated-orcid":false,"given":"Domingo","family":"Palacios\u2010Ce\u00f1a","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation Research Group of Humanities and Qualitative Research in Health Science, Universidad Rey Juan Carlos  Alcorc\u00f3n Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7580-9670","authenticated-orcid":false,"given":"Maria","family":"Salcedo\u2010Perez\u2010Juana","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation Research Group of Humanities and Qualitative Research in Health Science, Universidad Rey Juan Carlos  Alcorc\u00f3n Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0048-9358","authenticated-orcid":false,"given":"Maria","family":"Palacios\u2010Ce\u00f1a","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation Research Group of Humanities and Qualitative Research in Health Science, Universidad Rey Juan Carlos  Alcorc\u00f3n Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9431-6759","authenticated-orcid":false,"given":"Simona","family":"Giorgi","sequence":"additional","affiliation":[{"name":"Dravet Syndrome Foundation Spain  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-0209-3894","authenticated-orcid":false,"given":"Manuel","family":"Lorenzo\u2010Dieguez","sequence":"additional","affiliation":[{"name":"Epilepsy Unit, Neurology Department Blua Sanitas Valdebebas Hospital  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1511-5893","authenticated-orcid":false,"given":"Sanjay M","family":"Sisodiya","sequence":"additional","affiliation":[{"name":"UCL Queen Square Institute of Neurology, University College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6437-6758","authenticated-orcid":false,"given":"Cristina","family":"Garc\u00eda\u2010Bravo","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation Research Group of Humanities and Qualitative 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