{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T18:16:12Z","timestamp":1778696172472,"version":"3.51.4"},"reference-count":42,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T00:00:00Z","timestamp":1778198400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T00:00:00Z","timestamp":1778198400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Develop Med Child Neuro"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To identify and map current knowledge regarding early upper\u2010limb movement in infants from birth to 12\u2009months, which are indicative for development of unilateral spastic cerebral palsy (USCP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>A scoping review was conducted involving a comprehensive and systematic literature search in PubMed\/MEDLINE, Embase, and CINAHL. Articles were screened according to title and abstract and relevant data were extracted. Studies were eligible if they included infants aged 0 to 12\u2009months at risk of developing USCP and reported early upper\u2010limb movement characteristics indicative of USCP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twelve of 5482 studies were included. Three categories of assessments were recognized: (1) spontaneous upper\u2010limb movements; (2) pre\u2010reaching; and (3) upper\u2010limb skills. Across these categories, asymmetry was observed, namely in spontaneous wrist and digit movements, pre\u2010reaching trajectories, and reduced use of the contralesional hand in infants who developed USCP. From 15\u2009weeks of age onwards, asymmetry was more evident not only in upper\u2010limb movement patterns but also in object\u2010related upper\u2010limb skills.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interpretation<\/jats:title>\n                    <jats:p>Clinical signs of USCP in upper\u2010limb movements are noticeable from the age of 12\u2009weeks. Preceding signs may be subtle. Three\u2010dimensional motion analysis and wearable sensors may enhance early detection, enabling timely diagnosis and intervention.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dmcn.70304","type":"journal-article","created":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T09:51:56Z","timestamp":1778579516000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Upper\u2010limb movement in infants at risk for unilateral spastic cerebral palsy: A scoping review"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6266-5724","authenticated-orcid":false,"given":"Cornelia H.","family":"Verhage","sequence":"first","affiliation":[{"name":"Center for Child Development and Exercise, Wilhelmina Children's Hospital University Medical Center Utrecht, Utrecht University  Utrecht 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Utrecht  Utrecht Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niek E.","family":"Van Der Aa","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center Utrecht Utrecht University  Utrecht Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Van Brussel","sequence":"additional","affiliation":[{"name":"Center for Child Development and Exercise, Wilhelmina Children's Hospital University Medical Center Utrecht, Utrecht University  Utrecht 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