{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T23:36:01Z","timestamp":1790897761432,"version":"4.1.0"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,2,20]],"date-time":"2013-02-20T00:00:00Z","timestamp":1361318400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabet. Med."],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Despite the widespread assumption that adherence drives glycaemic control, there is little published support for this in Type\u00a02 diabetes. The study objective was to determine whether self\u2010reported medication adherence predicts future glycaemic control in Type\u00a02 diabetes, after accounting for baseline control.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Medication adherence (4\u2010item Morisky scale), glycaemic control (HbA<jats:sub>1c<\/jats:sub>%), and other variables were assessed in 287 adult primary care patients prescribed oral medication (40% also on insulin) for Type\u00a02 diabetes. Glycaemic control was reassessed 6\u00a0months later. Regression analyses examined concurrent and future glycaemic control as a function of baseline medication adherence after adjustment for baseline glycaemia and other potential confounders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Only half of patients reported high adherence. Cross\u2010sectional adjusted analysis replicated prior reports of an adherence\u2010HbA<jats:sub>1c<\/jats:sub> association (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.011). Even after adjusting for baseline HbA<jats:sub>1c<\/jats:sub>, each one\u2010point increase in baseline Morisky total score was associated with a 1.8\u00a0mmol\/mol (or 0.16%) increase in HbA<jats:sub>1c<\/jats:sub> measured 6\u00a0months later. Additionally, baseline endorsement of forgetting to take medication was associated with a 4.7\u00a0mmol\/mol (or 0.43%) increase in 6\u2010month HbA<jats:sub>1c<\/jats:sub> (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.005). This effect persisted after adjusting for psychological distress and did not vary by key demographic and medical features.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Even after stringent adjustment for baseline glycaemic control, self\u2010reported adherence to diabetes medication predicts long\u2010term glycaemic control. The Morisky scale is an easy\u2010to\u2010use clinical tool to identify patients whose glycaemic control will subsequently worsen, regardless of age, gender and psychological distress.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dme.12046","type":"journal-article","created":{"date-parts":[[2012,10,18]],"date-time":"2012-10-18T18:37:08Z","timestamp":1350585428000},"page":"338-344","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":95,"title":["Longitudinal association between medication adherence and glycaemic control in Type\u00a02 diabetes"],"prefix":"10.1111","volume":"30","author":[{"given":"J. E.","family":"Aikens","sequence":"first","affiliation":[{"name":"Department of Family Medicine University of Michigan Ann Arbor MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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