{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T00:46:20Z","timestamp":1787791580016,"version":"build-2784847793"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,11,16]],"date-time":"2013-11-16T00:00:00Z","timestamp":1384560000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabet. Med."],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>To determine the incidence and predictors of tendon ruptures requiring hospitalization of representative patients with Type 2 diabetes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 1296 patients from the longitudinal observational Fremantle Diabetes Study, Phase I, and 5159 de\u2010identified age\u2010 and sex\u2010matched control subjects without diabetes from the same urban area were studied. The patients' mean (<jats:sc>sd<\/jats:sc>) age was 64.0 (11.3) years and 48.6% of them were male. Their median (interquartile range) diabetes duration was 4.0 (1.0\u20139.0) years. The main outcome assessed was any tendon rupture requiring hospitalization in the Fremantle Diabetes Study subjects and the matched control subjects. Independent predictors of spontaneous ruptures in the patients from the Fremantle Diabetes Study were assessed using Cox proportional hazards modelling.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The incidence rate ratio for any tendon rupture requiring hospitalization in patients vs control subjects was 1.44 (95% CI 1.10\u20131.87; <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.005). Independent predictors of spontaneous ruptures in patients were <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> [hazard ratio 1.05 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.002\u20131.10] for 1\u00a0kg\/m<jats:sup>2<\/jats:sup> increase; <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.010] and alcohol consumption [hazard ratio 1.52 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.11\u20132.09) for \u221a1 standard drink\/day increase; <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.010]. Adjustment of the incidence rate ratio for overall rupture requiring hospitalization for these variables using the <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> and alcohol consumption data from the contemporary Australian general population suggested it could be as high as 1.84.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There is a greater risk of tendon rupture requiring hospitalization in people with Type 2 diabetes. Alcohol consumption and adiposity are potentially modifiable risk factors of spontaneous ruptures in patients with diabetes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dme.12344","type":"journal-article","created":{"date-parts":[[2013,10,23]],"date-time":"2013-10-23T22:27:15Z","timestamp":1382567235000},"page":"425-430","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":56,"title":["Incidence and predictors of hospitalization for tendon rupture in Type 2 diabetes: the Fremantle Diabetes Study"],"prefix":"10.1111","volume":"31","author":[{"given":"M. H. B.","family":"Zakaria","sequence":"first","affiliation":[{"name":"University of Western Australia School of Medicine and Pharmacology Fremantle Hospital Fremantle Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. A.","family":"Davis","sequence":"additional","affiliation":[{"name":"University of Western Australia School of Medicine and Pharmacology Fremantle Hospital Fremantle Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T. M. E.","family":"Davis","sequence":"additional","affiliation":[{"name":"University of Western Australia School of Medicine and Pharmacology Fremantle Hospital Fremantle Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,11,16]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.25.2.408"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.3113\/FAI.2008.0498"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiomech.2005.01.011"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1067-2516(97)80072-5"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/03008208808992789"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/03008209209014224"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0736-0266(03)00006-8"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/15438600490277860"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00767.2012"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.21327"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0032-1312672"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00402-010-1097-0"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jfas.2008.05.007"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001130050029"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00256-012-1504-4"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.2008.049320"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dys065"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.29.03.06.dc05-1567"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1071\/AH080766"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-12-0053"},{"key":"e_1_2_9_22_1","unstructured":"Australian Bureau of Statistics.National Nutrition Survey. Nutrient intakes and physical measurements. Australia.1995. Canberra; ABS 1998."},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/1478-7954-9-53"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/1071100713477621"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.2011.084079"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.27.11.2603"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00402-009-0877-x"},{"key":"e_1_2_9_28_1","first-page":"461","article-title":"Chronic alcohol consumption as a predisposing factor for multiple tendon ruptures in unusual sites in a patient with rheumatoid arthritis","volume":"25","author":"Bourikas LA","year":"2007","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.24518"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0004144"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jse.2009.04.006"}],"container-title":["Diabetic Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fdme.12344","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dme.12344","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T03:35:26Z","timestamp":1696217726000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/dme.12344"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11,16]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["10.1111\/dme.12344"],"URL":"https:\/\/doi.org\/10.1111\/dme.12344","archive":["Portico"],"relation":{},"ISSN":["0742-3071","1464-5491"],"issn-type":[{"value":"0742-3071","type":"print"},{"value":"1464-5491","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11,16]]},"assertion":[{"value":"2013-05-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-10-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-11-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}