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Whole\u2010organ pancreas transplantation is available in the UK, with ~200 transplants currently carried out per year. Patient survival and pancreas graft outcome rates are now similar to other solid organ transplant programmes, with high rates of long\u2010term insulin independence. In the present review, we will discuss whole\u2010pancreas transplantation as a treatment for diabetes, focusing on indications for transplantation, the nature of the procedure performed, graft survival rates and the consequences of pancreas transplantation on metabolic variables and the progression of diabetes\u2010related complications.<\/jats:p>","DOI":"10.1111\/dme.12373","type":"journal-article","created":{"date-parts":[[2013,12,7]],"date-time":"2013-12-07T05:08:00Z","timestamp":1386392880000},"page":"512-521","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Pancreas transplantation: a treatment option for people with diabetes"],"prefix":"10.1111","volume":"31","author":[{"given":"S.","family":"Mittal","sequence":"first","affiliation":[{"name":"Nuffield Department of Surgical Sciences Oxford UK"},{"name":"Oxford Centre of Diabetes Endocrinology and Metabolism Oxford UK"},{"name":"NIHR Oxford Biomedical Research Centre Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. 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