{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T06:17:12Z","timestamp":1777357032337,"version":"3.51.4"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,3,29]],"date-time":"2014-03-29T00:00:00Z","timestamp":1396051200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabet. Med."],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>To identify predictors of poor quality of life among men with diabetes from a comprehensive set of sexual, clinical, socio\u2010economic and lifestyle variables.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a cross\u2010sectional observational\u2010study of 253 men with Type\u00a02 diabetes, randomly selected from a clinic in Colombo, Sri Lanka. Erectile dysfunction was assessed using the five\u2010item International Index of Erectile Function and quality of life was assessed using the Sri Lankan version of the 36\u2010item short form health survey questionnaire and the disease\u2010specific Psychological Impact of Erectile Dysfunction scale. The presence of premature ejaculation, reduced libido, socio\u2010demographic and lifestyle data was obtained using an interviewer\u2010administered questionnaire. Significant predictors of quality of life were identified by stepwise multivariate linear regression models for short form\u201036 subscales, summary scales and two scales of Psychological Impact of Erectile Dysfunction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Significant predictors on the physical summary scale of the 36\u2010item short form were erectile dysfunction (\u03b2\u00a0 = \u00a07.93, 95% CI 3.70\u201312.17, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) and reduced libido (\u03b2\u00a0 = \u00a05.20, 95%\u00a0CI 0.82\u20139.59, <jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.05). Predictors on the mental health summary scale of the 36\u2010item short form were erectile dysfunction (\u03b2\u00a0=\u00a05.82, 95% CI 2.26\u20139.37, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.01), BMI &gt; 27.5\u00a0kg\/m<jats:sup>2<\/jats:sup> (\u03b2\u00a0 = \u00a09.12, 95% CI 1.38\u201317.44, <jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.05), ischaemic heart disease (\u03b2\u00a0 = \u00a06.39, 95% CI 0.74\u201312.04, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05) and insulin therapy (\u03b2\u00a0 = \u00a05.28, 95% CI 0.34\u201310.22, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). Significant predictors in the sexual experience scale of the Psychological Impact of Erectile Dysfunction were erectile dysfunction (\u03b2\u00a0=\u00a06.57, 95% CI 4.63\u20138.51, <jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001), reduced libido (\u03b2 =4.33, 95% CI 2.34\u20136.32, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) and postural hypotension (\u03b2\u00a0=\u00a03.99, 95% CI 0.13\u20137.85, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). Predictors on the emotional life scale of the Psychological Impact of Erectile Dysfunction were erectile dysfunction (\u03b2\u00a0=\u00a02.96, 95% CI 1.37\u20134.58, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001), reduced libido 2.75 (\u03b2\u00a0=\u00a02.75, 95% CI 1.12\u20134.40, <jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.01), younger age (\u03b2\u00a0 = \u00a01.05, 95% CI 0.35\u20131.75, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.01) and postural hypotension (\u03b2\u00a0 = \u00a03.39, 95% CI 0.35\u20136.45, <jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Erectile dysfunction was a strong predictor of poor generic and disease\u2010specific quality of life among other sexual and clinical variables in men with diabetes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dme.12412","type":"journal-article","created":{"date-parts":[[2014,2,17]],"date-time":"2014-02-17T18:40:59Z","timestamp":1392662459000},"page":"699-706","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Erectile dysfunction is a strong predictor of poor quality of life in men with Type 2 diabetes mellitus"],"prefix":"10.1111","volume":"31","author":[{"given":"L. S.","family":"Malavige","sequence":"first","affiliation":[{"name":"Oxford Centre for Diabetes Endocrinology and Metabolism Nuffield Department of Clinical Medicine University of Oxford Oxford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. D.","family":"Jayaratne","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine Faculty of Medical Science University of Sri Jayawardenapura Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. T.","family":"Kathriarachchi","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Faculty of Medical Science University of Sri Jayawardenapura Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Sivayogan","sequence":"additional","affiliation":[{"name":"Department of Community Medicine Faculty of Medical Science University of Sri Jayawardenapura Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Ranasinghe","sequence":"additional","affiliation":[{"name":"Department of Pharmacology Faculty of Medicine University of Colombo Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. C.","family":"Levy","sequence":"additional","affiliation":[{"name":"Oxford Centre for Diabetes Endocrinology and Metabolism Nuffield Department of Clinical Medicine University of Oxford Oxford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,3,29]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.27.7.1798"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.27.5.1047"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0885-3924(94)90129-5"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1520-7560(199905\/06)15:3<205::AID-DMRR29>3.0.CO;2-O"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1743-6109.2008.00907.x"},{"key":"e_1_2_8_7_1","first-page":"S54","article-title":"The role of the primary care clinician in the management of erectile dysfunction","volume":"4","author":"Sadovsky R","year":"2002","journal-title":"Rev Urol"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.25.2.284"},{"key":"e_1_2_8_9_1","first-page":"23","article-title":"Erectile dysfunction in diabetic men","volume":"24","author":"Kumar KV","year":"2004","journal-title":"Int J Diabetes Dev Ctries"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.3109\/09540261.2010.545987"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199303000-00006"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)64302-9"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijir.3900472"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000132159.61156.ea"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)15268-3"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc13-S011"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.21.2.231"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.160.9.1261"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.102.15.1773"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.160.12.1761"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(02)01606-0"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.75.880.83"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1080\/00926239008405254"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1743-6109.2008.00825.x"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-6-33"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2006.10.025"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2008.02523.x"}],"container-title":["Diabetic Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fdme.12412","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dme.12412","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T12:32:09Z","timestamp":1696249929000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/dme.12412"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,29]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["10.1111\/dme.12412"],"URL":"https:\/\/doi.org\/10.1111\/dme.12412","archive":["Portico"],"relation":{},"ISSN":["0742-3071","1464-5491"],"issn-type":[{"value":"0742-3071","type":"print"},{"value":"1464-5491","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,29]]},"assertion":[{"value":"2013-09-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-02-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-03-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}