{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T16:04:50Z","timestamp":1782230690584,"version":"3.54.5"},"reference-count":32,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2014,5,20]],"date-time":"2014-05-20T00:00:00Z","timestamp":1400544000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Steno Diabetes Center"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabet. Med."],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>To investigate the prevalence of symptomatic obstructive sleep apnoea in unselected patients with Type\u00a02 diabetes referred to a tertiary diabetes clinic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In a cross\u2010sectional design, all newly referred patients were offered a stepwise screening for obstructive sleep apnoea with: (1) The Berlin questionnaire; then, if indicative: (2) overnight home monitoring with the ApneaLink<jats:sup>\u2122<\/jats:sup> device. Patients with an apnoea\u2013hypopnoea index \u2265\u00a05\/h were offered referral for diagnostic polygraphy and treatment initiation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 200 patients participated (61% men; age 59.6\u00a0\u00b1\u00a010.5\u00a0years, diabetes duration 8.3\u00a0\u00b1\u00a06.3\u00a0years and <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> 31.7\u00a0\u00b1\u00a06.7\u00a0kg\/m<jats:sup>2<\/jats:sup>). According to the questionnaire, 106 patients showed \u2018high risk\u2019 of obstructive sleep apnoea, and 72 of these were referred to polygraphy based on ApneaLink screening corresponding to a prevalence of symptomatic obstructive sleep apnoea of 39%. Patients with symptomatic obstructive sleep apnoea had significantly higher <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>, poorer glycaemic control and lower plasma <jats:styled-content style=\"fixed-case\">HDL<\/jats:styled-content> cholesterol levels as compared with patients unlikely to have obstructive sleep apnoea. The groups were not different with respect to sex, age, diabetes duration, blood pressure, diabetic complications or medication use. In multiple regression analyses, age, <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">HDL<\/jats:styled-content> cholesterol levels were all significant, independent predictors of obstructive sleep apnoea.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>At least one third of people with Type\u00a02 diabetes referred to a diabetes clinic in Denmark has symptomatic obstructive sleep apnoea. Our data suggest higher age, a compromised plasma lipid profile and a more obese phenotype in patients with Type\u00a02 diabetes who have obstructive sleep apnoea, highlighting the need to focus on screening and treatment of obstructive sleep apnoea in these patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dme.12477","type":"journal-article","created":{"date-parts":[[2014,4,28]],"date-time":"2014-04-28T08:48:41Z","timestamp":1398674921000},"page":"1460-1467","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["At least one in three people with Type\u00a02 diabetes mellitus referred to a diabetes centre has symptomatic obstructive sleep apnoea"],"prefix":"10.1111","volume":"31","author":[{"given":"H.","family":"Storgaard","sequence":"first","affiliation":[{"name":"Steno Diabetes Center Gentofte Denmark"},{"name":"Center for Diabetes Research Gentofte Hospital University of Copenhagen Gentofte 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