{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:48:09Z","timestamp":1787014089266,"version":"build-2736575974"},"reference-count":28,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2014,11,16]],"date-time":"2014-11-16T00:00:00Z","timestamp":1416096000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabet. Med."],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Coeliac disease is an autoimmune disorder classically characterized by gastrointestinal symptoms and poor growth. The disease can be difficult to recognize in patients with Type\u00a01 diabetes mellitus. Some clinicians find treatment of the disease in asymptomatic individuals controversial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case reports<\/jats:title>\n                    <jats:p>Two adolescent female patients with Type\u00a01 diabetes experienced recurrent hypoglycaemic seizures. Neither patient reported gastrointestinal symptoms or poor growth. After diagnosis and treatment of coeliac disease, hypoglycaemia resolved.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>These cases illustrate how frequent unexplained severe hypoglycaemia can be an atypical presentation of coeliac disease in youth with Type\u00a01 diabetes. Furthermore, they emphasize the importance of screening and treatment of coeliac disease in asymptomatic patients with Type\u00a01 diabetes. Although controversial, management of coeliac disease in these asymptomatic patients can prevent the vicious cycle of recurrent hypoglycaemia and decrease risk for morbidity and death.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dme.12488","type":"journal-article","created":{"date-parts":[[2014,5,7]],"date-time":"2014-05-07T14:23:49Z","timestamp":1399472629000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Coeliac disease presenting as severe hypoglycaemia in youth with Type\u00a01 diabetes"],"prefix":"10.1111","volume":"31","author":[{"given":"N.","family":"Khoury","sequence":"first","affiliation":[{"name":"Department of Metabolism and Endocrinology Washington University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Semenkovich","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Washington University in St Louis St Louis MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. M.","family":"Arbel\u00e1ez","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Washington University in St Louis St Louis MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,11,16]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.26.6.1932"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5448.2009.00573.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1155\/2010\/161285"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e31821a23d0"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.27.6.1294"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2012.03720.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpediatrics.2007.38"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.113.5.1254"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.2006.048876"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-200501000-00001"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5448.2009.00573.x"},{"issue":"589","key":"e_1_2_7_13_1","first-page":"e2","article-title":"Anthropometry, metabolic control, and follow\u2010up in children and adolescents with type\u00a01 diabetes mellitus and biopsy\u2010proven celiac disease","volume":"158","author":"Frohlich\u2010Reiterer EE","year":"2011","journal-title":"J Pediatr"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-200101000-00012"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/dme.12329"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc11-0149"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2013.09.005"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0b013e3182496a25"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11892-013-0376-x"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/67.3.477"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001250051593"},{"key":"e_1_2_7_22_1","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.2337\/diacare.21.8.1379b","article-title":"Hypoglycemia and reduction of the insulin requirement as a sign of celiac disease in children with IDDM","volume":"21","author":"Iafusco D","year":"1998","journal-title":"Diabetes Care"},{"key":"e_1_2_7_23_1","volume-title":"Hypoglycemia in Diabetes: Pathophysiology, Prevalence and Prevention","author":"Cryer P","year":"2009"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5448.2007.00274.x"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(99)70211-8"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/pedi.12088"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5448.2009.00588.x"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc10-2164"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2007.05.028"}],"container-title":["Diabetic Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fdme.12488","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fdme.12488","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/dme.12488","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T03:44:07Z","timestamp":1696304647000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/dme.12488"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11,16]]},"references-count":28,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["10.1111\/dme.12488"],"URL":"https:\/\/doi.org\/10.1111\/dme.12488","archive":["Portico"],"relation":{},"ISSN":["0742-3071","1464-5491"],"issn-type":[{"value":"0742-3071","type":"print"},{"value":"1464-5491","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11,16]]},"assertion":[{"value":"2013-12-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-04-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-11-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}