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Screening of participants recruited to the Adolescent type 1 Diabetes cardio\u2010renal Intervention Trial (Ad<jats:styled-content style=\"fixed-case\">DIT<\/jats:styled-content>) confirms that these early changes in albumin excretion are related to both diabetic nephropathy and cardiovascular risk; in part, independent of glycaemic control. Thus, as well as current attempts to improve glycaemic control through enhanced targeted insulin delivery, pumps, sensors and closed loop, we have explored the role of angiotensin\u2010converting enzyme inhibitors and statins in providing cardio\u2010renal protection during adolescence.<\/jats:p>","DOI":"10.1111\/dme.13299","type":"journal-article","created":{"date-parts":[[2016,12,15]],"date-time":"2016-12-15T14:47:11Z","timestamp":1481813231000},"page":"460-466","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["<i>Banting Memorial Lecture 2016<\/i> Reducing lifetime risk of complications in adolescents with Type 1 diabetes"],"prefix":"10.1111","volume":"34","author":[{"given":"D. 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