{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T09:19:44Z","timestamp":1793783984951,"version":"4.6.1"},"reference-count":34,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2019,6,5]],"date-time":"2019-06-05T00:00:00Z","timestamp":1559692800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000361","name":"Diabetes UK","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000361","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabet. Med."],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To estimate the healthcare costs of diabetic foot disease in England.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patient\u2010level data sets at a national and local level, and evidence from clinical studies, were used to estimate the annual cost of health care for foot ulceration and amputation in people with diabetes in England in 2014\u20132015.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The cost of health care for ulceration and amputation in diabetes in 2014\u20132015 is estimated at between \u00a3837 million and \u00a3962 million; 0.8% to 0.9% of the National Health Service (\n                      <jats:styled-content style=\"fixed-case\">NHS<\/jats:styled-content>\n                      ) budget for England. More than 90% of expenditure was related to ulceration, and 60% was for care in community, outpatient and primary settings. For inpatients, multiple regression analysis suggested that ulceration was associated with a length of stay 8.04 days longer (95% confidence interval 7.65 to 8.42) than that for diabetes admissions without ulceration.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Diabetic foot care accounts for a substantial proportion of healthcare expenditure in England, more than the combined cost of breast, prostate and lung cancers. Much of this expenditure arises through prolonged and severe ulceration. If the\n                      <jats:styled-content style=\"fixed-case\">NHS<\/jats:styled-content>\n                      were to reduce the prevalence of diabetic foot ulcers in England by one\u2010third, the gross annual saving would be more than \u00a3250 million. Diabetic foot ulceration is a large and growing problem globally, and it is likely that there is potential to improve outcomes and reduce expenditure in many countries.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/dme.13973","type":"journal-article","created":{"date-parts":[[2019,4,20]],"date-time":"2019-04-20T00:15:10Z","timestamp":1555719310000},"page":"995-1002","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":407,"title":["The cost of diabetic foot ulcers and amputations to the National Health Service in England"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0412-7255","authenticated-orcid":false,"given":"M.","family":"Kerr","sequence":"first","affiliation":[{"name":"Insight Health Economics Ltd London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Barron","sequence":"additional","affiliation":[{"name":"Public Health England London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Chadwick","sequence":"additional","affiliation":[{"name":"College of Podiatry London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Evans","sequence":"additional","affiliation":[{"name":"Public Health England London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. 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