{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T18:44:31Z","timestamp":1771526671451,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,1,15]],"date-time":"2020-01-15T00:00:00Z","timestamp":1579046400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001648","name":"European Foundation for the Study of Diabetes","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001648","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007028","name":"Leona M. and Harry B. Helmsley Charitable Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007028","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diabet. Med."],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To compare clinical characteristics and outcomes in adults with type 1 diabetes aged \u2265\u00a060\u00a0years using continuous subcutaneous insulin infusion (CSII) vs. insulin injection therapy. Further, to determine the percentage of older adults with type 1 diabetes using CSII.<\/jats:p><\/jats:sec><jats:sec><jats:title>Research design and methods<\/jats:title><jats:p>Retrospective study using data of the Diabetes Prospective Follow\u2010up Registry (DPV). Including percentage CSII use from 2008 to 2018, and the characteristics of 9547 individuals extracted from the DPV in March 2019 (<jats:italic>N<\/jats:italic> = 1404 CSII; <jats:italic>N<\/jats:italic> = 8143 insulin injection therapy). Wilcoxon rank sum tests were used for continuous variables and chi\u2010square tests for categorical variables to compare clinical characteristics of people using CSII vs. insulin injection therapy. Adjusted analyses used generalized linear models to compare diabetes\u2010related outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>CSII usage has increased in older adults (from 12% in 2008 to 23% in 2018). After adjustment, CSII was associated with lower HbA<jats:sub>1c<\/jats:sub> [60.7\u00a0mmol\/mol (7.7\u00a0\u00b1\u00a00.1%) vs. 62.8% (7.9\u00a0\u00b1\u00a00.1%)], lower daily insulin dose (0.49\u00a0\u00b1\u00a00.02 vs. 0.61\u00a0\u00b1\u00a00.01\u00a0IU\/kg), fewer days in hospital (8.1\u00a0\u00b1\u00a00.12 vs. 11.2\u00a0\u00b1\u00a00.11\u00a0days\/person\u2010year), fewer severe hypoglycaemic events (0.16\u00a0\u00b1\u00a00.02 vs. 0.21\u00a0\u00b1\u00a00.03 events\/person\u2010year) and fewer diabetic ketoacidosis (0.06\u00a0\u00b1\u00a00.01 vs. 0.08\u00a0\u00b1\u00a00.01\u00a0events\/person\u2010year). Individuals on CSII showed lower rates of microalbuminuria and also have a diagnosis of depression and neuropathy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A growing number of older adults are using insulin pumps. Older age in itself should not be seen as a contraindication for CSII.<\/jats:p><\/jats:sec>","DOI":"10.1111\/dme.14218","type":"journal-article","created":{"date-parts":[[2019,12,19]],"date-time":"2019-12-19T02:06:30Z","timestamp":1576721190000},"page":"856-862","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Comparative characteristics of older people with type 1 diabetes treated with continuous subcutaneous insulin infusion or insulin injection therapy: data from the German\/Austrian DPV registry"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5894-6734","authenticated-orcid":false,"given":"J.","family":"Grammes","sequence":"first","affiliation":[{"name":"Health Psychology Institute of Psychology Johannes Gutenberg University Mainz Germany"},{"name":"Diabetes Technology Working Group Ulm Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"K\u00fcstner","sequence":"additional","affiliation":[{"name":"Diabetes Technology Working Group Ulm Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Dapp","sequence":"additional","affiliation":[{"name":"Diabetes Center Hospital District Tuttlingen Medical Clinic Spaichingen Spaichingen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Hummel","sequence":"additional","affiliation":[{"name":"Diabetology Outpatient Clinic Rosenheim Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.\u2010C.","family":"K\u00e4mmer","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Cardiology, Diabetology and Geriatrics Vivantes Klinikum Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0095-9265","authenticated-orcid":false,"given":"T.","family":"Kubiak","sequence":"additional","affiliation":[{"name":"Health Psychology Institute of Psychology Johannes Gutenberg University Mainz Germany"},{"name":"Diabetes Technology Working Group Ulm Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Sch\u00fctz\u2010Fuhrmann","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Krankenhaus Hietzing Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Zimny","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Endocrinology and Diabetology Helios Kliniken Schwerin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Bollow","sequence":"additional","affiliation":[{"name":"ZIBMT Institute of Epidemiology and Medical Biometry University of Ulm Ulm Germany"},{"name":"German Center for Diabetes Research (DZD) Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.W.","family":"Holl","sequence":"additional","affiliation":[{"name":"ZIBMT Institute of Epidemiology and Medical Biometry University of Ulm Ulm Germany"},{"name":"German Center for Diabetes Research (DZD) Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"for the DPV initiative","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,1,15]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0113635"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1037\/a0040383"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001742"},{"key":"e_1_2_10_5_1","unstructured":"Insulin Pump Market Prospect Share Development Growth and Demand Forecast to 2022 2017. 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